A novel red fluorescent and dynamic nanocomposite hydrogel based on chitosan and alginate doped with inclusion complex of carbon dots

Abstract: Abstract Recent advancements in biomaterials have profoundly transformed the fields of dermatology and tissue engineering, etc., offering innovative solutions that markedly improve skin treatment outcomes. This review provides a comprehensive overview of the latest developments in natural, synthetic, and composite biomaterials tailored for skin treatments and skin‐related medical devices, including wound healing, tissue engineering, drug delivery, dermatological therapies, medical aesthetics, e‐skin, and skin‐related surgery‐assistant devices. The incorporation of artificial intelligence (AI) into biomaterial design has facilitated the development of adaptive and predictive systems capable of responding dynamically to the skin's physiological needs. Moreover, an in‐depth understanding of the interactions between biomaterials and cells, as well as the activation of biological pathways and regulation of cellular processes is pivotal for enhancing skin health and function. Looking forward, the main efforts toward future in this field are suggested as follows: 1) Development of novel materials remains central; 2) Responsive biomaterials enable precise therapy; 3) Integration with cell therapy is pivotal in regenerative medicine; 4) In‐depth investigations into material‐driven biological mechanisms are critical for innovative design of skin‐related materials; 5) Interdisciplinary collaboration is vital for the rapid evolution of biomaterials; 6) Enhanced applications of AI is driving the development of adaptive and predictive biomaterials.

TL;DR: A critical review of the current state of self-healing injectable hydrogels for tissue regeneration and a practical guide for their rheological analysis are provided to showcase their applicability for regeneration of various tissues and 3D printing of complex tissues and organoids.

TL;DR: Antimicrobial tests for mycelial growth reduction under atmospheric conditions proved the fungistatic behaviour of the inclusion complexes against Botrytis cinerea.

TL;DR: In this paper, a simple one-pot microwave-assisted green-synthesis route for the fabrication of bright red-luminescent graphene quantum dots (GQDs) using ethanolic extracts of Mangifera indica (mango) leaves was reported.

TL;DR: In this article, the authors provide an updated roadmap of the hetero-atom-doped carbon dots and provide an outlook towards future developments of these photoluminescent materials.