Journal Article10.1016/S0272-6386(97)90021-4
A new classification for renal defects in net acid excretion
Kamel S. Kamel,Luis F. Briceno,Marta I. Sanchez,Luis Brenes,Peter D. Yorgin,Sang Whay Kooh,J. Williamson Balfe,Mitchell L. Halperin +7 more
TL;DR: An alternative classification of the group of disorders called renal tubular acidosis is proposed, one that is based on the component of net acid excretion that is abnormal, and a term that describes the renal handling of metabolizable organic anions is suggested.
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About: This article is published in American Journal of Kidney Diseases. The article was published on 01 Jan 1997. The article focuses on the topics: Net acid excretion & Renal tubular acidosis.
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Citations
Metabolic acidosis: pathophysiology, diagnosis and management
TL;DR: Adverse effects of acute metabolic acidosis primarily include decreased cardiac output, arterial dilatation with hypotension, altered oxygen delivery, decreased ATP production, predisposition to arrhythmias, and impairment of the immune response.
Renal tubular acidosis.
Sebastian A,Morris Rc +1 more
TL;DR: This chapter outlines renal tubular mechanisms mediating bicarbonate reabsorption by the nephron and acid secretion by the kidney and the pathologies that disturb them and highlights a diagnostic approach to and treatment for them.
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Fluid, electrolyte and acid–base disorders associated with antibiotic therapy
TL;DR: The mechanisms that disrupt renal tubular function are described and Integrated with the physiology of each successive nephron segment, the receptors, transporters, channels or pores that are affected by antibiotics are discussed.
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Studies on the pathophysiology of the low urine pH in patients with uric acid stones.
TL;DR: It is speculated that an alkaline proximal tubular cell pH could be the basis for the low NH(+)(4) and high citrate excretions in 10 of 12 patients in group 2.
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Differential Diagnosis of Nongap Metabolic Acidosis: Value of a Systematic Approach
TL;DR: This review summarizes current information concerning the pathophysiology of this electrolyte pattern and the value and limitations of all of the diagnostic studies available and provides a systematic and cost-effective approach to the differential diagnosis of nongap metabolic acidosis.
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The use of the urinary anion gap in the diagnosis of hyperchloremic metabolic acidosis.
TL;DR: The use of the urinary anion gap, as a rough index of urinary ammonium, may be helpful in the initial evaluation of hyperchloremic metabolic acidosis.
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