A neurogenetic approach to impulsivity.
Eliza Congdon,Turhan Canli +1 more
TL;DR: This article will review the current state of the field with respect to the neural and genetic basis of trait impulsivity and show that individual differences in personality traits can be related to individual differences within specific genes.
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Abstract: Impulsivity is a complex and multidimensional trait that is of interest to both personality psychologists and to clinicians For investigators seeking the biological basis of personality traits, the use of neuroimaging techniques such as positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) revolutionized personality psychology in less than a decade Now, another revolution is under way, and it originates from molecular biology Specifically, new findings in molecular genetics, the detailed mapping and the study of the function of genes, have shown that individual differences in personality traits can be related to individual differences within specific genes In this article, we will review the current state of the field with respect to the neural and genetic basis of trait impulsivity
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Citations
Physical pain and impulsivity in alcohol-dependent patients
Andrzej Jakubczyk,Kirk J. Brower,Maciej Kopera,Aleksandra Krasowska,Aneta Michalska,Agata Łoczewska,Aleksandra Majewska,Mark A. Ilgen,Sylwia Fudalej,Marcin Wojnar +9 more
TL;DR: Investigation of relationships between different dimensions of impulsivity and the current experience of physical pain in individuals entering alcohol treatment found physical pain is an independent correlate of both subjectively reported and objectively measured levels of impulsiveness.
9
Association between the catechol-O-methyltransferase (COMT) Val158Met polymorphism and manual aiming control in healthy subjects.
Guilherme Menezes Lage,Débora Marques de Miranda,Marco Aurélio Romano-Silva,Simone Becho Campos,Maicon Rodrigues Albuquerque,Humberto Correa,Leandro Fernandes Malloy-Diniz +6 more
TL;DR: This study found a significant association between the COMT polymorphism and manual aiming control and these findings indicate that individual differences in motor control require further investigation using genetic studies.
Allelic variation in dopamine D2 receptor gene is associated with attentional impulsiveness on the Barratt Impulsiveness Scale (BIS-11).
Jasmine B. Taylor,Tarrant Cummins,Allison M. Fox,Beth Patricia Johnson,Janette Tong,Troy A. W. Visser,Ziarih Hawi,Mark A. Bellgrove +7 more
TL;DR: Findings provide preliminary evidence that allelic variation in DRD2 may influence impulsiveness by increasing the propensity for attentional lapses, as measured by the BIS-11.
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Testing differential susceptibility: Plasticity genes, the social environment, and their interplay in adolescent response inhibition
Jennifer S. Richards,Alejandro Arias Vasquez,Daan van Rooij,Dennis van der Meer,Barbara Franke,Pieter J. Hoekstra,Dirk J. Heslenfeld,Jaap Oosterlaan,Stephen V. Faraone,Catharina A. Hartman,Jan K. Buitelaar +10 more
TL;DR: While a pattern of differential genetic susceptibility was found, more clarity on the role of the FG during response inhibition is warranted before firm conclusions can be made.
References
Lifetime Prevalence and Age-of-Onset Distributions of DSM-IV Disorders in the National Comorbidity Survey Replication
Ronald C. Kessler,Patricia A. Berglund,Olga Demler,Robert Jin,Kathleen R. Merikangas,Ellen E. Walters +5 more
TL;DR: Lifetime prevalence estimates are higher in recent cohorts than in earlier cohorts and have fairly stable intercohort differences across the life course that vary in substantively plausible ways among sociodemographic subgroups.
20.4K
Prevalence, Severity, and Comorbidity of 12-Month DSM-IV Disorders in the National Comorbidity Survey Replication
TL;DR: Although mental disorders are widespread, serious cases are concentrated among a relatively small proportion of cases with high comorbidity, as shown in the recently completed US National Comorbidities Survey Replication.
Factor structure of the Barratt impulsiveness scale.
TL;DR: The results of the present study suggest that the total score of the BIS-11 is an internally consistent measure of impulsiveness and has potential clinical utility for measuring impulsiveness among selected patient and inmate populations.
Behavioral inhibition, sustained attention, and executive functions: Constructing a unifying theory of ADHD.
TL;DR: A theoretical model that links inhibition to 4 executive neuropsychological functions that appear to depend on it for their effective execution is constructed and finds it to be strongest for deficits in behavioral inhibition, working memory, regulation of motivation, and motor control in those with ADHD.
Epigenetic programming by maternal behavior.
Ian C. G. Weaver,Nadia Cervoni,Frances A. Champagne,Ana C. D'Alessio,Shakti Sharma,Jonathan R. Seckl,Sergiy Dymov,Moshe Szyf,Michael J. Meaney +8 more
TL;DR: It is shown that an epigenomic state of a gene can be established through behavioral programming, and it is potentially reversible, suggesting a causal relation among epigenomicState, GR expression and the maternal effect on stress responses in the offspring.