Journal Article10.1111/J.1432-1033.1994.00883.X
A model for the denaturation and aggregation of beta-lactoglobulin.
TL;DR: A quantitatively correct kinetic model for the temperature-induced denaturation and aggregation of beta-lactoglobulin is presented and recognizes an initiation, a propagation and a termination step by analogy with polymer radical chemistry.
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Abstract: A quantitatively correct kinetic model for the temperature-induced denaturation and aggregation of beta-lactoglobulin is presented. The model recognizes an initiation, a propagation and a termination step by analogy with polymer radical chemistry. The decrease in native beta-lactoglobulin is predicted to follow order 3/2, in agreement with experimental results. The size of the protein polymer particles is predicted to be proportional to the square root of the initial beta-lactoglobulin concentration. The scattered light intensity is proportional to the product of concentration and size of the protein polymer particles. The initial increase in scattering intensity of the particles therefore scales with the initial squared beta-lactoglobulin concentration. The influence of other reaction conditions, e.g. ionic strength and pH, can be incorporated via the reaction constants of the reaction kinetic pathway.
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Citations
Thermal Denaturation and Aggregation of Whey Proteins
Marcia Esparza
- 01 Jan 2022
TL;DR: In this article , a good understanding of protein structure and effect of thermal treatment can help find a way to improve the thermal stability of whey protein, a co-product of cheese making and caseinate production.
Heat-induced aggregation kinetics of potato protein - Investigated by chromatography, calorimetry, and light scattering.
TL;DR: In this paper , the heat-induced aggregation behavior of patatin rich potato protein isolate (PPI) was investigated by reversed-phase high-pressure liquid chromatography (RP-HPLC), differential scanning calorimetry (DSC), and dynamic light scattering.
Molecular differences in the formation and structure of fine-stranded and particulate beta-lactoglobulin gels.
Thierry Lefèvre,Muriel Subirade +1 more
TL;DR: An Fourier transform infrared spectroscopic study of the thermal behavior of beta-lactoglobulin (beta-lg) in salt-free D(2)O solutions and low ionic strength at different pDs reveals differences between fine-stranded and particulate gels.
Separation of the effects of denaturation and aggregation on whey-casein protein interactions during the manufacture of a model infant formula
TL;DR: In this paper, the effects of denaturation and aggregation of whey protein on the physicochemical characteristics during processing of a model IMF were examined, and the results showed that aggregation is more influential than denaturation in determining viscosity development during HTST treatment of IMF, and that such viscoity development can be controlled by altering protein-protein interactions using, for example, pre-heat treatment of protein ingredients.
Separation of Whey Protein Aggregates by Means of Continuous Centrifugation
Nicole Haller,Ulrich Kulozik +1 more
TL;DR: In this paper, the applicability of decanter centrifuges for high efficient separation of valuable proteins from whey was investigated, and two different types of protein aggregates, α-lactalbumin (α-la) and β -lactoglobulin (β-lg), were produced by means of selective thermal aggregation.
References
Principles of Polymer Chemistry.
TL;DR: A good introduction to the history of the POLYMER CHEMISTRY can be found in this paper, where the authors present a good overview of the history and history of their work.
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Light Scattering by Small Particles
H. C. Van de Hulst,V. Twersky +1 more
TL;DR: Light scattering by small particles as mentioned in this paper, Light scattering by Small Particle Scattering (LPS), Light scattering with small particles (LSC), Light Scattering by Small Parts (LSP),
10.4K
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Light Scattering by Small Particles
H. C. van de Hulst
- 01 Dec 1981
TL;DR: Light scattering by small particles as mentioned in this paper, Light scattering by Small Particle Scattering (LPS), Light scattering with small particles (LSC), Light Scattering by Small Parts (LSP),
7.9K
The structure of β -lactoglobulin and its similarity to plasma retinol-binding protein
Miroslav Z. Papiz,Lindsay Sawyer,Elias Eliopoulos,Anthony C.T. North,John B. C. Findlay,R. Sivaprasadarao,T.A. Jones,M. E. Newcomer,P. J. Kraulis +8 more
TL;DR: A possible binding site for retinol in BLG has been identified by model-building and a role for BLG in vitamin A transport is suggested and specific receptors for the BLG–retinol complex in the intestine of neonate calves are discovered.
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