Journal Article10.1016/J.COPBIO.2008.07.008
A green light for engineered algae: redirecting metabolism to fuel a biotechnology revolution
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TL;DR: Ongoing advances in cultivation techniques coupled with genetic manipulation of crucial metabolic networks will further promote microalgae as an attractive platform for the production of numerous high-value compounds.
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About: This article is published in Current Opinion in Biotechnology. The article was published on 01 Oct 2008.
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Citations
Chlamydomonas starchless mutant defective in ADP-glucose pyrophosphorylase hyper-accumulates triacylglycerol.
Yantao Li,Danxiang Han,Guongrong Hu,David Dauvillée,Milton Sommerfeld,Steven G. Ball,Qiang Hu +6 more
TL;DR: It is demonstrated that inactivation of ADP-glucose pyrophosphorylase in a Chlamydomonas starchless mutant led to a 10-fold increase in TAG, suggesting that shunting of photosynthetic carbon partitioning from starch to TAG synthesis may represent a more effective strategy than direct manipulation of the lipid synthesis pathway to overproduce TAG.
392
Choreography of Transcriptomes and Lipidomes of Nannochloropsis Reveals the Mechanisms of Oil Synthesis in Microalgae.
Jing Li,Danxiang Han,Dongmei Wang,Kang Ning,Jing Jia,Li Wei,Xiaoyan Jing,Shi Huang,Jie Chen,Yantao Li,Qiang Hu,Jian Xu +11 more
TL;DR: The temporal and spatial regulation model of oil accumulation in microalgae provides a basis for improving the understanding of TAG synthesis in microalga and will also enable more rational genetic engineering of TAG production.
Extraction of Bio-oils from Microalgae
TL;DR: This review discusses existing extraction methodologies as they have and can be applied to microalgae and their potential as a unit operation that exists within the framework of an industrial‐scale microalgal cultivation process that extends from the production of biomass in photobioreactors to the fractionation of the recovered bio‐oil.
376
Fatty acids profiling: A selective criterion for screening microalgae strains for biodiesel production
Ahmad Farhad Talebi,Seyed Kaveh Mohtashami,Meisam Tabatabaei,Masoud Tohidfar,Abdolreza Bagheri,Mehrshad Zeinalabedini,Hossein Hadavand Mirzaei,Mehrdad Mirzajanzadeh,Saeid Malekzadeh Shafaroudi,Shiva Bakhtiari +9 more
TL;DR: This study is the first to report on the isolation process and lipid profile analysis of algal strains obtained from the Persian Gulf as well as 9 previously introduced strains, finding the highest volumetric lipid productivity was found in Chlorella vulgaris.
376
Microalgal bioreactors: Challenges and opportunities
TL;DR: There are distinct advantages to using closed systems, but technical challenges still remain, and development of a more controllable, economical, and efficient closed culturing system is needed.
364
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