Journal Article10.1016/0022-2836(70)90057-4
A general method applicable to the search for similarities in the amino acid sequence of two proteins
TL;DR: A computer adaptable method for finding similarities in the amino acid sequences of two proteins has been developed and it is possible to determine whether significant homology exists between the proteins to trace their possible evolutionary development.
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About: This article is published in Journal of Molecular Biology. The article was published on 28 Mar 1970. The article focuses on the topics: BLOSUM & Structural alignment.
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Citations
LigPlot+: multiple ligand-protein interaction diagrams for drug discovery.
TL;DR: A graphical system for automatically generating multiple 2D diagrams of ligand-protein interactions from 3D coordinates that facilitates popular research tasks, such as analyzing a series of small molecules binding to the same protein target, a single ligand binding to homologous proteins, or the completely general case where both protein and ligand change.
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Nuclear ribosomal internal transcribed spacer (ITS) region as a universal DNA barcode marker for Fungi
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TL;DR: Among the regions of the ribosomal cistron, the internal transcribed spacer (ITS) region has the highest probability of successful identification for the broadest range of fungi, with the most clearly defined barcode gap between inter- and intraspecific variation.
References
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Atlas of protein sequence and structure
M. A. Chang,M. O. Dayhoff,R. V. Eck,M. R. Sochard +3 more
- 01 Jan 1965
An improved method of testing for evolutionary homology.
TL;DR: A more sensitive method of searching for a homologous relation between two proteins is presented and results for α - and β -hemoglobin, for which the homology is already known, are presented and shown to be consistent.
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