A general method applicable to the search for similarities in the amino acid sequence of two proteins

TL;DR: These analyses reveal somatic mutations in chromatin-regulating genes MLL, M LL2, MLL3 and ARID1A in 20% of patients that are associated with improved survival and have implications for new avenues of therapeutic intervention.

TL;DR: It is shown how pattern discovery can be used to automatically acquire lexical entities directly from an untranscribed audio stream by exploiting the structure of repeating patterns within the speech signal.

TL;DR: The results establish Ser/Thr/Tyr phosphorylation as a common posttranslational modification in Eubacteria, present since the onset of cellular life and demonstrated that bacterial phosphoproteins and phosphorylated residues are significantly more conserved than their nonphosphorylated counterparts.

TL;DR: The cloning of a Leishmania chagasi antigen gene and an evaluation of leishmaniasis patient antibody responses to the recombinant protein, rK39, show that rK 39 may replace crude parasite antigens as a basis for serological diagnosis of visceral leish maniasis.

TL;DR: A more sensitive method of searching for a homologous relation between two proteins is presented and results for α - and β -hemoglobin, for which the homology is already known, are presented and shown to be consistent.