Journal Article10.1016/0006-2952(74)90235-4
A fluorometric micromethod for the simultaneous determination of serotonin, noradrenaline and dopamine in milligram amounts of brain tissue
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TL;DR: A miniaturized method for the assay of serotonin, noradrenaline and dopamine in extracts from l.5 to 5 mg of brain tissue (rat and mouse) was developed and permitted quantification and spectral analysis of pmole amounts of the amines.
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About: This article is published in Biochemical Pharmacology. The article was published on 01 Sep 1974.
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Citations
Strain differences in responsiveness of norepinephrine-sensitive adenosine 3',5'-monophosphate-generating systems in rat brain slices after intraventricular administration of 6-hydroxydopamine.
Phil Skolnick,John W. Daly +1 more
TL;DR: There may be a limit to the responsiveness of catecholamine-sensitive cyclic AMP generating systems which can develop following alterations in synaptic input, as shown in brain slices of Sprague-Dawley and F-344 rats.
11
Aging Related Changes of Retina and Optic Nerve of Uromastyx aegyptia and Falco tinnunculus
TL;DR: It is concluded that aging showed an inverse relationship with the neurotransmitters and antioxidant enzymes and a linear relationship of caspases, malondialdhyde, DNA apoptosis, and P53 markers of cell death that reflected the retinal cytological alterations and lipofuscin accumulation within inner segments.
11
In vivo effects of benztropine and nomifensine on dopamine and noradrenaline terminals in rat brain.
TL;DR: It is concluded that amphetamine, desipramine and nomifensine all had an effect on the uptake mechanism in noradrenergic terminals and that in addition nom ifensine had a releasing effect on these terminals.
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Persistent hypotensive effect of L-dopa given early during development to rats with inherited stress-induced arterial hypertension.
Naumenko Ev,Maslova Ln,Nikolai I. Gordienko,Sergey Y. Amstyslavski,Nikolai N. Dygalo,A. L. Markel +5 more
TL;DR: A long-lasting decrease of the basal and stress- induced arterial blood pressure was obtained in rats with inherited emotional stress-induced arterial hypertension by means of injections of the dopamine precursor L-DOPA during early development.
10
Beneficial effect of aspirin against interferon‐α‐2b—induced depressive behavior in Sprague Dawley rats
Shailendra Bhatt,Kilambi Pundarikakshudu,Paresh U. Patel,Nirav Patel,Ashish K. Panchal,Gaurang B. Shah,Sunita Goswami +6 more
TL;DR: Aspirin can serve as a potential antidepressant both individually and as adjuvant agent in the treatment of depression, and inhibition of the cyclo‐oxygenase‐2 levels and prostaglandins concentration or any other potential physiological and biochemical mechanisms may be involved in antidepressant effect.
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TL;DR: A fluorimetric method for the determination of dopamine using differences in fluorescence characteristics at pH about 5.3, microquantities of dopainine can be determined in the presence of at least equal amounts of adrenaline or noradrenaline.
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A sensitive method for spectrophotofluorometric assay of catecholamines.
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A method for the determination of serotonin and norepinephrine in discrete areas of rat brain.
TL;DR: A method for the determination of both serotonin (5HT) and norepinephrine (NE) in small samples of brain is described, applicable to as little as 50 mg of brain tissue.
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A method for the determination of 3,4-dihydroxyphenylalanine (DOPA) in brain.
TL;DR: The method is an extension of the chromatographic separation procedure for 5-HIAA and 5-HTP published by Lindqvist (1971) and 9 different compounds can be estimated after a single column procedure.
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