A comprehensive overview of radioguided surgery using gamma detection probe technology
Stephen P. Povoski,Ryan L. Neff,Cathy Mojzisik,David M. O'Malley,George H. Hinkle,Nathan Hall,Douglas A Murrey,Michael V. Knopp,Edward W. Martin +8 more
TL;DR: In the current review, this work has attempted to comprehensively evaluate the history, technical aspects, and clinical applications of radioguided surgery using gamma detection probe technology.
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Abstract: The concept of radioguided surgery, which was first developed some 60 years ago, involves the use of a radiation detection probe system for the intraoperative detection of radionuclides. The use of gamma detection probe technology in radioguided surgery has tremendously expanded and has evolved into what is now considered an established discipline within the practice of surgery, revolutionizing the surgical management of many malignancies, including breast cancer, melanoma, and colorectal cancer, as well as the surgical management of parathyroid disease. The impact of radioguided surgery on the surgical management of cancer patients includes providing vital and real-time information to the surgeon regarding the location and extent of disease, as well as regarding the assessment of surgical resection margins. Additionally, it has allowed the surgeon to minimize the surgical invasiveness of many diagnostic and therapeutic procedures, while still maintaining maximum benefit to the cancer patient. In the current review, we have attempted to comprehensively evaluate the history, technical aspects, and clinical applications of radioguided surgery using gamma detection probe technology.
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•Journal Article
Technique du ganglion sentinelle appliquée aux cancers de l’utérus : étude préliminaire
Loïc Lelievre,Sophie Camatte,Marie-Aude Le Frère-Belda,Khaldoun Kerrou,Marc Froissart,Roland Taurelle,Vildé F,Fabrice Lecuru +7 more
TL;DR: Cette technique pourrait eviter des curages etendus inutiles et permettrait une meilleure evaluation lymphatique d’optimiser le diagnostic des metastases and des micrometastases lymphatiques dans les stades precoces.
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Radioguided localization of clinically occult breast lesions (ROLL): a pilot study.
TL;DR: The data suggest that ROLL offer a simple and reliable method to localize occult breast lesions, allowing complete removal of the lesion in 100% of the patients and is safe for both patients and the medical staff, producing less discomfort in patients than wire localization.
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The evolution of the management of regional lymph nodes in melanoma.
TL;DR: The advent of sentinel node biopsy has radically changed the approach to melanoma, with patients without evidence of nodal metastases being considered for elective lymph node dissection.
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Radioimmunoguided surgery of colorectal carcinoma with an 111In-labelled anti-TAG72 monoclonal antibody.
Africa Muxi,F. Pons,Sergi Vidal-Sicart,Francisco Javier Setoain,R Herranz,Novell F,R Fernández,M Trias,J. Setoain +8 more
TL;DR: Radioimmunoguided surgery, as a complementary technique to RIS, is particularly useful in recurrences and can help the surgeon in the resection of small tumour deposits which are difficult to localize.
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