A comprehensive overview of radioguided surgery using gamma detection probe technology
Stephen P. Povoski,Ryan L. Neff,Cathy Mojzisik,David M. O'Malley,George H. Hinkle,Nathan Hall,Douglas A Murrey,Michael V. Knopp,Edward W. Martin +8 more
TL;DR: In the current review, this work has attempted to comprehensively evaluate the history, technical aspects, and clinical applications of radioguided surgery using gamma detection probe technology.
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Abstract: The concept of radioguided surgery, which was first developed some 60 years ago, involves the use of a radiation detection probe system for the intraoperative detection of radionuclides. The use of gamma detection probe technology in radioguided surgery has tremendously expanded and has evolved into what is now considered an established discipline within the practice of surgery, revolutionizing the surgical management of many malignancies, including breast cancer, melanoma, and colorectal cancer, as well as the surgical management of parathyroid disease. The impact of radioguided surgery on the surgical management of cancer patients includes providing vital and real-time information to the surgeon regarding the location and extent of disease, as well as regarding the assessment of surgical resection margins. Additionally, it has allowed the surgeon to minimize the surgical invasiveness of many diagnostic and therapeutic procedures, while still maintaining maximum benefit to the cancer patient. In the current review, we have attempted to comprehensively evaluate the history, technical aspects, and clinical applications of radioguided surgery using gamma detection probe technology.
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TL;DR: The laparoscopic SN procedure appears to reliably predict the metastatic status of the regional lymphatic basin in patients with cervical cancer.
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Comparison of image quality of different iodine isotopes (I-123, I-124, and I-131)
Erwann Rault,Stefaan Vandenberghe,Roel Van Holen,Jan De Beenhouwer,Steven Staelens,Ignace Lemahieu +5 more
TL;DR: This study aimed to compare the image quality that can be achieved by three iodine isotopes: I-131 and I-123 for single-photon emission computed tomography imaging, andI-124 for positron emission tomography Imaging and found that I-124 gave the best imaging properties owing to its electronic collimation and a short coincidence time window.
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Limited pelvic lymphadenectomy using the sentinel lymph node procedure in patients with localised prostate carcinoma: a pilot study.
Isabelle Brenot-Rossi,Cyril Bastide,Stéphane Garcia,Stephane Dumas,Benjamin Esterni,Jacques Pasquier,Dominique Rossi +6 more
TL;DR: The sentinel lymph node (SLN) procedure revealed the individual variability in the lymphatic drainage of the prostate and could assist in the correct staging of patients with early prostate cancer, especially when performing limited lymphadenectomy.
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