6-(Or 8)-[[(substituted amino)alkyl]oxy(or thio)]-3,4-dihydro-4-phenyl-2(1H)-quinolinones

TL;DR: Alkyne compounds having MCH-receptor antagonistic activity are useful for preparing pharmaceutical compositions for the treatment of metabolic disorders and/or eating disorders, particularly obesity and diabetes as mentioned in this paper.

TL;DR: In this article, the antihistaminic properties of carbostyril derivatives and their salts have been studied and the properties of antihistamine agents have been discussed, represented by the general formula (1), where R1 is a hydrogen atom, a lower alkenyl group, lower alkynyl group or lower alkyl group which may have phenyl group(s) as the substituted groups.

TL;DR: Six new tertiary amine derivatives of cinnamic acid, phenylpropionic acid, sorbic acid and hexanoic acid were designed, synthesized and evaluated for the effect on AChE and BChE in vitro to reveal the most potent inhibitory activity of these derivatives.

TL;DR: The carbostyril derivatives and their pharmaceutically acceptable salts represented by the formula (1) are useful as the active ingredient in cardiotonic compositions as discussed by the authors, where R 1 is a hydrogen atom, R 2 and R 3 form, together with the adjacent nitrogen atom and further with an additional oxygen atom, a 5- or 6-membered saturated heterocyclic ring which may have a lower alkyl group or a phenyl-lower alkyal group as the substituent.

TL;DR: A 3-PHENYL-4-ACYLOXYCARBOSTYRIL of the FormulA: 2-(O=),3-phenyl,4-(R-COO-)-1,2-DIHYDROQUINOLINE whereIN R is METHYL OR ETHOXY PREPARED by TREATING 3PHENyl 4-HYDROCarBOXTYRIL with an ACYLATING AGENT, WHICH IS USEFUL AS A MINOR TRAQUILIZER with LESS SIDE EFFECT and