23Na MR Imaging at 7 T after Knee Matrix–associated Autologous Chondrocyte Transplantation Preliminary Results
Siegfried Trattnig,Goetz H. Welsch,Vladimir Juras,Pavol Szomolanyi,Marius E. Mayerhoefer,David Stelzeneder,Tallal C. Mamisch,Oliver Bieri,Klaus Scheffler,Stefan Zbýn +9 more
TL;DR: With the modified 3D GRE sequence at 7 T, a sufficiently high SNR in sodium images was achieved, allowing for differentiation of repaired tissue from native cartilage after MACT, and a strong correlation was found between sodium imaging and dGEMRIC in patients after Mact.
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Abstract: To evaluate the feasibility of sodium 7-T magnetic resonance (MR) imaging in repaired tissue and native cartilage of patients after matrix-associated autologous chondrocyte transplantation (MACT) and compare results with delayed gadolinium-enhanced MR imaging of cartilage (dGEMRIC) at 3 T.
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Pros and cons of ultra-high-field MRI/MRS for human application.
Mark E. Ladd,Peter Bachert,Peter Bachert,Martin Meyerspeer,Ewald Moser,Armin M. Nagel,Armin M. Nagel,David G. Norris,David G. Norris,Sebastian Schmitter,Sebastian Schmitter,Oliver Speck,Sina Straub,Moritz Zaiss +13 more
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Sodium MRI: Methods and applications
TL;DR: An up-to-date review of the theoretical background, the methodology, the challenges, limitations, and current and potential new applications of sodium MRI is presented.
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7-T MR—from research to clinical applications?
TL;DR: Examples are given to demonstrate the advantages of susceptibility‐weighted imaging, time‐of‐flight MR angiography, high‐resolution functional MRI, 1H and 31P MRSI in the human brain, sodium and functional imaging of cartilage and the first results using an eight‐channel body array, suggesting future areas of research should be intensified in order to fully explore the potential of 7‐T MR systems for use in clinical diagnosis.
Cartilage and meniscal T2 relaxation time as non-invasive biomarker for knee osteoarthritis and cartilage repair procedures
Thomas Baum,Gabby B. Joseph,Dimitrios C. Karampinos,Pia M. Jungmann,Thomas M. Link,Jan S. Bauer +5 more
TL;DR: It was demonstrated that cartilage and meniscal T2 relaxation time values were significantly increased in subjects with compared to those without radiographic OA and focal knee lesions, respectively, indicating that T1 relaxation time may be a reliable discriminatory biomarker.
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MRI at 7 tesla and above: Demonstrated and potential capabilities
TL;DR: This overview article focuses on already achieved advantages for in vivo imaging, i.e., in imaging the brain and joints of the musculoskeletal system, but also considers developments in body imaging, which is particularly challenging.
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Stefan Nehrer,Stefan Nehrer,Howard A. Breinan,Arun J. Ramappa,H.-P. Hsu,Tom Minas,Sonya Shortkroff,Clement B. Sledge,Ioannis V. Yannas,Myron Spector,Myron Spector +10 more
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