Open Access
2012 Revised International Chapel Hill Consensus Conference Nomenclature of
John Charles Jennette,Ronald Falk,Neil Basu,Maria C. Cid,Franco Ferrario,Luis Felipe Flores-Suárez,W. L. Gross,Loïc Guillevin,E. C. Hagen,Peter Lamprecht,Raashid Luqmani,Seza Ozen,Andrew J. Rees,Scott Dgi,Ulrich Specks,Kei Takahashi,Richard A. Watts +16 more
- 01 Jan 2012
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TL;DR: In this article, the running head is assigned to one of the following candidates:Jennette JC, Falk RJ, Bacon PA, Basu N, Cid MC, Ferrario F, Ferrardo F, Flores-Suarez LF, Gross WL, Guillevin L, Hagen EC, Hoffman GS, Jayne DR, Kallenberg CGM, Lamprecht P, Langford CA, Luqmani RA, Mahr AD, Matteson EL, Merkel PA, Ozen S, Pusey CD, Rasmussen N, Rees
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Abstract: Jennette JC, Falk RJ, Bacon PA, Basu N, Cid MC, Ferrario F, Flores-Suarez LF, Gross WL, Guillevin L, Hagen EC, Hoffman GS, Jayne DR, Kallenberg CGM, Lamprecht P, Langford CA, Luqmani RA, Mahr AD, Matteson EL, Merkel PA, Ozen S, Pusey CD, Rasmussen N, Rees AJ, Scott DGI, Specks U, Stone JH, Takahashi K, Watts RA. Running Head:
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TL;DR: The characteristics of pediatric cases of eosinophilic granulomatosis with polyangiitis (EGPA), a systemic necrotizing vasculitis rarely diagnosed in children, are described and compared with adult cases included in the French Vasculitis Study Group cohort.
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TL;DR: The IL- 6R antibody may be more effective in mitigating vascular inflammation and remodeling than CTX via inhibition of IL-6 and MMP-9 through inhibition of interleukin and cytokine levels.
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Microscopic polyangiitis: Clinical characteristics and long-term outcomes of 378 patients from the French Vasculitis Study Group Registry.
Yann Nguyen,Christian Pagnoux,Alexandre Karras,Thomas Quemeneur,François Maurier,Mohamed Hamidou,Alain Le Quellec,Noémie Jourde Chiche,Pascal Cohen,Alexis Régent,François Lifermann,Arsène Mekinian,Chahéra Khouatra,Eric Hachulla,Jacques Pourrat,Marc Ruivard,Pascal Godmer,Jean-François Viallard,Benjamin Terrier,Luc Mouthon,Loïc Guillevin,Xavier Puéchal +21 more
TL;DR: Non-renal manifestations and several risk factors for death or relapse were frequent in this nationwide cohort of patients with microscopic polyangiitis, suggesting that MPA management can be further improved.
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References
Nomenclature of systemic vasculitides. Proposal of an international consensus conference
Jc Jennette,Ronald J. Falk,K Andrassy,Pa Bacon,J Churg,J Churg,Wl Gross,Wl Gross,E. C. Hagen,Gs Hoffman,Gg Hunder,Cgm Kallenberg,Rt Mccluskey,Ra Sinico,Ra Sinico,Aj Rees,La Vanes,R Waldherr,Allan Wiik +18 more
TL;DR: The following are some of the conclusions and proposals made at the Chapel Hill Consensus Conference on the Nomenclature of Systemic Vasculitis.
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The American College of Rheumatology 1990 criteria for the classification of giant cell arteritis
Gene G. Hunder,Gene G. Hunder,Daniel A. Bloch,Daniel A. Bloch,Beat A. Michel,Mary Betty Stevens,Mary Betty Stevens,William P. Arend,William P. Arend,Leonard H. Calabrese,Leonard H. Calabrese,Steven M. Edworthy,Steven M. Edworthy,Anthony S. Fauci,Anthony S. Fauci,Randi Y. Leavitt,J. T. Lie,J. T. Lie,Robert W. Lightfoot,Robert W. Lightfoot,Alfonse T. Masi,Alfonse T. Masi,Dennis J. McShane,Dennis J. McShane,John A. Mills,John A. Mills,Stanley L. Wallace,Stanley L. Wallace,Nathan J. Zvaifler,Nathan J. Zvaifler +29 more
TL;DR: Criteria for the classification of giant cell (temporal) arteritis were developed by comparing 214 patients who had this disease with 593 patients with other forms of vasculitis, and 2 other variables were included: scalp tenderness and claudication of the jaw or tongue or on deglutition.
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The American College of Rheumatology 1990 criteria for the classification of Takayasu arteritis.
William P. Arend,Beat A. Michel,Daniel A. Bloch,Gene G. Hunder,Leonard H. Calabrese,Steven M. Edworthy,Anthony S. Fauci,Randi Y. Leavitt,J. T. Lie,Robert W. Lightfoot,Alfonse T. Masi,Dennis J. McShane,John A. Mills,Mary Betty Stevens,Stanley L. Wallace,Nathan J. Zvaifler +15 more
TL;DR: Criteria for the classification of Takayasu arteritis were developed by comparing 63 patients who had this disease with 744 control patients with other forms of vasculitis, and the presence of 3 or more of these 6 criteria demonstrated a sensitivity of 90.5% and a specificity of 97.0%.
2.2K
The Pathophysiology of IgA Nephropathy
Hitoshi Suzuki,Krzysztof Kiryluk,Jan Novak,Zina Moldoveanu,Andrew B. Herr,Matthew B. Renfrow,Robert J. Wyatt,Francesco Scolari,Jiri Mestecky,Ali G. Gharavi,Bruce A. Julian +10 more
TL;DR: Recent advances in understanding the biochemical, immunologic, and genetic pathogenesis of IgA nephropathy are discussed, and five distinct susceptibility loci are identified that potentially influence these processes and contain candidate mediators of disease.
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