TL;DR: In order to understand trends in incidence of MT, variation in blood utilization and patient outcomes, and to harmonize research outcomes, a standard and universally accepted definition of MT is urgently required.

TL;DR: Findings demonstrate the importance of monitoring transfusion-related adverse reactions to track the safety of platelet transfusions and quantify the impact of mitigation strategies through national hemovigilance systems.

TL;DR: In this article, the authors discuss the use of 4F-PCC in four critical bleeding settings: cardiac surgery, major trauma, end-stage liver disease, and oral anti-Xa reversal.

TL;DR: In this article, the authors evaluated the evidence of a difference in outcomes of potential "all-cause" harm in the transfusion of whole blood (WB) compared to blood components (BC) for any bleeding patient regardless of age or clinical condition.

TL;DR: Findings support the use of guidelines developed in Europe and the United States for East Asian pediatric recipients for transfusion-related alloimmunization among neonates, children, and adolescents in Japan.

TL;DR: A review of the evidence for and against platelet transfusion in the neonate is presented in this paper, where the authors identify areas of future potential neonatal platelet transplant research.

TL;DR: RHFerrara et al. as discussed by the authors developed a modern, elaborate database for D variants, thanks to an extensive literature search with meticulous curation of 387 peer-reviewed articles and 80 abstracts from major conferences.

TL;DR: Daratumumab (DARA) is the first-in-class therapy targeting CD38 expressing-plasma cells (PC) and plasma blasts and has been used for the treatment of multiple myeloma and other hematologic malignancies as mentioned in this paper.

TL;DR: This article conducted a meta-analysis of randomized controlled trials (RCTs) with trial sequential analysis to investigate whether convalescent plasma is futile in reducing mortality in patients hospitalized with COVID-19.

TL;DR: The second largest US blood center reported the non-vaccine seroprevalence of total immunoglobulin directed against the S1 spike protein of SARS-CoV-2 in their donors.

TL;DR: In this paper, the authors performed an observational cohort study from June 15th to November 30th, 2020 on a population of 1.531 million blood donors tested for antibodies to SARS-CoV-2 by person, place, time, ABO group and dynamics of test reactivity.

TL;DR: In this paper, the authors presented an inductive computational method to make sense of vast amounts of dynamic unstructured blood donation text data that exists on social media, and applied structural topic modeling on 7 years of Dutch blood donation Facebook and Twitter data by the general public.

TL;DR: In this article, the authors performed comprehensive literature search in MEDLINE and EMBASE databases to study important outcomes of immunoadsorption as adjunctive treatment in patients with acquired hemophilia.

TL;DR: ABO-incompatible plasma transfusion in the form of group A plasma and/or low titer group O whole blood for trauma patients of unknown ABO group was examined in this paper.

TL;DR: In this paper, the authors conducted a systematic review of the literature to identify the role of both regional oxygenation and/or ultrasound-based perfusion monitoring as a potential trigger to initiate packed red blood cell transfusion in anaemic preterm infants.

TL;DR: A systematic review and meta-analysis was performed according to published guidelines to assess the false positive rate and influencing factors in platelet transfusion-associated mortality as mentioned in this paper, and the combined aerobic/anaerobic FPR was 2.4 events per thousand (EPT) with a prediction interval of 0.5 to 5.5 EPT.

TL;DR: Fibrinogen is a key coagulation protein that is necessary for the formation of stable clots and has received a great deal of attention over the last 10 - 15 years.

TL;DR: The effectiveness of monetary incentives to increase altruistic behavior is in dispute as discussed by the authors, as it could decrease altruistic motivations of voluntary donors (motivational crowding-out) or decrease blood quality (increase transmittable infectious disease risks).

TL;DR: The role of viscoelastic testing in the evaluation and management of traumatic brain injury (TBI) remains a subject of ongoing exploration as mentioned in this paper, highlighting four key publications that provide significant insights into this subject.

TL;DR: The following selection of important publications address the current state of hemostatic resuscitation strategies in pediatric trauma patients as well as the remaining knowledge gaps and areas for further research.

TL;DR: In this paper, the authors evaluated the association between the NRBC count and hematopoietic progenitor cell (HPC) content (TNC and CD34+ cell counts) in Korean full-term newborn CBUs.

TL;DR: In this article, an English language literature search was conducted for cases of babesiosis treated with Red Cell Exchange (RCE) since 1980 and relevant laboratory and clinical outcome data were extracted.

TL;DR: In this paper, the authors summarise key concepts in cryobiology and recent advances in the field of stem cell transplantation, including transient warming events and thawing of HSC grafts.

TL;DR: Predictive accuracy for commonly used point-of-care devices for coagulopathic bleeding in cardiac surgery did not demonstrate predictive accuracy, however, the certainty of the evidence was low and studies reporting the highest values for sensitivity and specificity had important methodological limitations.