TL;DR: Examination of intestinal tract mucosa from 44 infants and children who died suddenly and unexpectedly in northeastern Texas showed the cecum and appendix to have the highest concentration of eosinophils and relatively low counts in the stomach and distal large intestine, which correlates with the impression that increased numbers of eOSinophil are a common feature of otherwise unremarkable pediatric endoscopic biopsies.

TL;DR: It is concluded that cytokeratin immunostains can be helpful in distinguishing metastatic colonic adenocarcinoma from primary ovarian carcinomas, particularly endometrioid carcinomas.

TL;DR: It is suggested that VMC, in the absence of APKD, are a manifestation of a different disease, which could be genetic or secondary to inflammation or ischemia.

TL;DR: A review of the literature indicates that asymptomatic infection, ureteric stricture and hemorrhagic cystitis are other possible manifestations of polyoma virus in the human urogenital tract.

TL;DR: The findings concerning the expression of immunohistochemical CK are considered to be useful in addition to the diagnostic criteria when making a differential diagnosis of primary and metastatic carcinomas of the liver.

TL;DR: This work focuses on the application of the fractal approach to measuring irregular and complex features of pathologic cells and tissues and also on its potential role in the understanding of tumor biology.

TL;DR: Clinopathologic information from 16 cases combined with the 8 previously reported examples confirms that TCC-NV is a persistent and aggressive neoplasm notable for its innocuous appearance in histologic preparations.

TL;DR: Data indicate that MPC is present in up to 24.1% of thyroids removed for unrelated thyroid disease, and the predominance of this lesion in men is in striking contrast to the occurrence of clinically significant thyroid cancer, suggesting that the initiation of carcinogenesis is not sexually dimorphic, whereas promoters of tumor growth are.

TL;DR: Although the term desmoplastic fibroblastoma has been applied to this neoplasm, it is thought that the name collagenous fibroma is more appropriate for these tumors.

TL;DR: These findings provide histopathologic evidence of downstaging in axillary lymph nodes and of relative treatment resistance by intraductal and intralymphatic tumor and emphasize the need for pathologic staging in patients with Stage T1-T3 lesions.

TL;DR: Results indicate that c-myc amplification in HCC can be evaluated by differential PCR of needle biopsy specimens, and is an unfavorable prognostic indicator.

TL;DR: Results strongly suggest that disseminated serous carcinomas, whether primary in the ovary, endometrium, or peritoneum, are of monoclonal rather than multicentric origin; that bilateral stage III ovarian cancers are typically of monOClonal origin; and that additional genetic events involving p53 might occur during progression of these tumors.

TL;DR: The variability of the diagnosis of high-grade prostatic intraepithelial neoplasia was related to the level of interest in prostatic pathology, the conditions of the study, the subjective application of diagnostic criteria, and the influence of peers and clinical colleagues.

TL;DR: The findings suggest that microstaging of early invasive bladder cancer is technically difficult and, at least in cases derived from various urologists and laboratories, does not yield a prognostically significant separation.

TL;DR: It is concluded that positive immunoreactivity for A1AT and CD68 in GCT may be a reflection of the intracytoplasmic accumulation of phagolysosomes and that it does not imply a histiocytic origin for this tumors.

TL;DR: The gross circumscription of the adenomyomas, their polypoid appearance, the frequent lobular arrangement of glands, the absence of invasive glands with a desmoplastic stromal reaction, and lack of even focal atypia were the most helpful findings in differentiating these tumors from adenoma malignum.

TL;DR: A significant proportion of patients with PTLD expressed lytic nucleic acids and proteins, and lytic activity was highest in patients with multisite disease, although this difference was not statistically significant.

TL;DR: In urinary bladder transitional cell carcinoma, CD44s and CD44v6 expression parallels that for other cell adhesion molecules that feature a significant progressive loss of immunoreactivity in association with tumor dedifferentiation, advancing pathologic stage, and abnormal DNA content.

TL;DR: Although ITAC and colorectal adenocarcinoma are histologically similar, there are important differences at the genetic level based on expression of K-ras-2 and p53 abnormalities.

TL;DR: It was found that the number of newly formed vessels was significantly associated with poor prognosis only in medullary carcinoma, and microvessel count, as quantitation of tumor angiogenesis, plays an important prognostic role in medULLary thyroid carcinomas.

TL;DR: Large, well-circumscribed, solid, tan tumor showed histologic similarity to developing metanephric tubular epithelium and expressed proximal tubule marker URO-2 and wt1 gene protein product, commonly expressed in Wilms' tumors.

TL;DR: Bcl-2 apparently plays no role in the progression of atypical hyperplasia to carcinoma or in the development of high-grade or advanced-stage endometrial carcinoma, and the marked difference in b cl-2 expression in hyperplastic and atypicallyHyperplastic glands might prove to be diagnostically useful in the often difficult distinction of these entities.

TL;DR: It is important that in studies evaluating the frequency of nodal involvement by serous borderline tumors, intranodal mesothelial cells should not be misinterpreted as metastatic borderline tumor, a distinction that can be difficult with only routinely stained sections.

TL;DR: The present study shows that adrenal lymphoma is EBV associated and has a B-cell phenotype and clinical and pathologic findings were summarized.

TL;DR: Results indicate that the MIC2 antibody is a useful method by which to distinguish ES from a variety of other round cell lesions that may be encountered in the sinonasal region.

TL;DR: There was no correlation between expression of these markers and tumor size or nodal status, although loss of CD44v6 was associated with lymph node metastases in the TC group only, and in the spectrum of neuroendocrine tumors of the lung, p53 and bcl-2 overexpression correlates with more aggressive histologic cell types.

TL;DR: The results suggest that HPV plays a role in the development of both LP and NIP, and that similar viral types (i.e., HPV6 and HPV11) may exhibit relative differences in their tissue specificity.

TL;DR: Analysis of immunohistochemical stains and electron microscopic analysis support the presumed mesothelial derivation of adenomatoid tumors of the adrenal gland as metastatic or primary malignant vascular tumors.