About: Medical Recapitulate is an academic journal. The journal publishes majorly in the area(s): Cancer & Traditional Chinese medicine. Over the lifetime, 605 publications have been published receiving 1159 citations.
TL;DR: In this paper, a review of sensory and motility disorders of the upper GI tract in diabetes is discussed; and the morphological changes and biomechanical remodeling related to the sensory-motor dysfunction is also addressed.
Abstract: Gastrointestinal (GI) sensory-motor abnormalities are common in patients with diabetes mellitus and may involve any part of the GI tract. Abnormalities are frequently sub-clinical, and fortunately only rarely do severe and life-threatening problems occur. The pathogenesis of abnormal upper GI sensory-motor function in diabetes is incompletely understood and is most likely multi-factorial of origin. Diabetic autonomic neuropathy as well as acute suboptimal control of diabetes has been shown to impair GI motor and sensory function. Morphological and biomechanical remodeling of the GI wall develops during the duration of diabetes, and may contribute to motor and sensory dysfunction. In this review sensory and motility disorders of the upper GI tract in diabetes is discussed; and the morphological changes and biomechanical remodeling related to the sensory-motor dysfunction is also addressed.
TL;DR: Some researches show that gene Hes-1 and Hes-5 are basic effective factors in Notch pathway,by which nevous cell differentiation can be mediated, which will result in the severe deformity in tissue and organ morphology.
Abstract: In the development of nervouse system,many kinds of neurons and glial cells are differentiated from common precursor cells.In this course,cell-cell interaction mediated by Notch can maintain cell splitting and diversity in its types.Activated Notch can inhibite cell differentiation.Abnormal pathway of Notch can result in premature differentiation of mervous cell and deficiency in cell types,which will result in the severe deformity in tissue and organ morphology.Some researches show that gene Hes-1 and Hes-5 are basic effective factors in Notch pathway,by which nevous cell differentiation can be mediated.
TL;DR: Long-acting bronchodilators, alone or combined with inhaled corticosteroids, and long-term using of macrolides can suppress exacerbations by bronchial colonisation.
Abstract: Exacerbations are frequently seen events in the evolution of chronic obstructive pulmonary disease(COPD),which may lead to hospital admission and even result in death.Therefore,optimizing treatment for stable COPD will help to reduce exacerbations.Long-acting bronchodilators,alone or combined with inhaled corticosteroids,have now been demonstrated efficacy in reducing the rate of exacerbations in patients with COPD.And long-term using of macrolides can suppress exacerbations by bronchial colonisation.Non-pharmacological interventions such as rehabilitation and daily physical activity are also useful strategies to prevent exacerbations in patients with COPD and should be implemented in clinical practice.
TL;DR: It is showed that it will be better to the pregnancy obesity by controlling the weight gain or keeping invariant during the period of generation.
Abstract: With the increasing pregnancy obesity,the poor outcome is thought highly of a dramatic problem.This article summarized the physiology,pathological change,and the risk during gestation period,birth process,and long-term after delivery associated to the pregnancy obesity and showed that it will be better to the pregnancy obesity by controlling the weight gain or keeping invariant during the period of generation.