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  3. Mayo Clinic Proceedings: Innovations, Quality & Outcomes
  4. 2021
Showing papers in "Mayo Clinic Proceedings: Innovations, Quality & Outcomes in 2021"
Journal Article•10.1016/J.MAYOCPIQO.2021.01.009•
Thromboinflammatory Biomarkers in COVID-19: Systematic Review and Meta-analysis of 17,052 Patients.

[...]

Rahul Chaudhary1, Rahul Chaudhary2, Jalaj Garg3, Damon E. Houghton2, M. Hassan Murad2, Ashok Kondur, Rohit Chaudhary4, Waldemar E. Wysokinski2, Robert D. McBane2 •
University of Pittsburgh1, Mayo Clinic2, Medical College of Wisconsin3, Deakin University4
08 Feb 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: Thrombo-inflammatory biomarkers (D-dimer, Fibrinogen, CRP, hs-CRP, ferritin, and IL-6) and marker of end-organ damage (hs-Troponin I) are associated with increased severity and mortality in COVID-19 infection.

68 citations

Journal Article•10.1016/J.MAYOCPIQO.2021.01.015•
Clinical and Economic Burden of Stroke Among Young, Midlife, and Older Adults in the United States, 2002-2017.

[...]

Safi U. Khan1, Muhammad Zia Khan1, Muhammad U. Khan1, Muhammad Shahzeb Khan2, Mamas A. Mamas3, Mamas A. Mamas4, Muhammad Rashid3, Ron Blankstein5, Salim S. Virani6, Michelle C. Johansen7, Michael D. Shapiro8, Michael J. Blaha7, Miguel Cainzos-Achirica9, Farhaan S Vahidy9, Khurram Nasir9 •
West Virginia University1, John H. Stroger, Jr. Hospital of Cook County2, Keele University3, Thomas Jefferson University4, Brigham and Women's Hospital5, Baylor College of Medicine6, Johns Hopkins University7, Wake Forest University8, Houston Methodist Hospital9
01 Apr 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: Stroke-related hospitalization and health care expenditure are increasing in the United States, particularly among young and midlife adults, and a higher cost of stay counterbalances the benefits of reducing stroke and mortality in older patients.

55 citations

Journal Article•10.1016/J.MAYOCPIQO.2020.10.005•
Cardiac Toxicity of Chloroquine or Hydroxychloroquine in Patients With COVID-19: A Systematic Review and Meta-regression Analysis.

[...]

Imad M. Tleyjeh, Zakariya Kashour1, Oweida Aldosary, Muhammad Riaz2, Haytham Tlayjeh3, Musa A. Garbati4, Rana Tleyjeh5, Mouaz H. Al-Mallah6, M. Rizwan Sohail7, Dana Gerberi7, Aref A. Bin Abdulhak, John R. Giudicessi7, Michael J. Ackerman7, Tarek Kashour8 •
University of Alberta1, Quaid-i-Azam University2, King Abdulaziz Medical City3, University of Maiduguri4, Alfaisal University5, Houston Methodist Hospital6, Mayo Clinic7, King Saud University8
01 Feb 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: Treatment of COVID-19 patients with CQ or HCQ is associated with a significant risk of drug-induced QT prolongation and relatively higher incidence of TdP/VT/cardiac arrest, and these agents should not be used routinely in the management of CO VID-19 disease.

51 citations

Journal Article•10.1016/J.MAYOCPIQO.2020.09.016•
Financial Conflicts of Interest in Clinical Practice Guidelines: A Systematic Review

[...]

Sahar Tabatabavakili1, Sahar Tabatabavakili2, Rishad Khan2, Michael A. Scaffidi3, Michael A. Scaffidi1, Nikko Gimpaya1, David Lightfoot1, Samir C. Grover1, Samir C. Grover2 •
St. Michael's Hospital1, University of Toronto2, Queen's University3
19 Jan 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: There are numerous FCOI among authors of CPGs, many of which are undisclosed, and a significant difference inFCOI prevalence based on types of FCOi and CPG sponsor society is found.

49 citations

Journal Article•10.1016/J.MAYOCPIQO.2021.05.005•
Cancer Mortality Rates Increasing vs Cardiovascular Disease Mortality Decreasing in the World: Future Implications.

[...]

Karim ReFaey1, Shashwat Tripathi1, Shashwat Tripathi2, Sanjeet S. Grewal1, Adip G. Bhargav1, David J. Quinones3, Kaisorn L. Chaichana1, Samuel O. Antwi1, Leslie T. Cooper1, Fredric B. Meyer1, Roxana S. Dronca1, Robert B. Diasio1, Alfredo Quiñones-Hinojosa •
Mayo Clinic1, Northwestern University2, Florida State University3
01 Jun 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: In this article, the authors analyzed mortality rates for cancer and cardiovascular disease by calculating age-standardized mortality rates (ASRs) from 2000 to 2015 for high-income, upper-middle income, and lower-middle-income countries.

38 citations

Journal Article•10.1016/J.MAYOCPIQO.2021.03.007•
Anti-Inflammatory treatment of COVID-19 pneumonia with tofacitinib alone or in combination with dexamethasone is safe and possibly superior to dexamethasone as a single agent in a predominantly African American cohort.

[...]

Maroun E. Hayek, Michael Mansour, Harrison Ndetan1, Quentin Burkes, Robert Corkern, Ammar Dulli, Reya Hayek2, Karim Parvez, Satwinder Singh •
University of Texas Health Science Center at Tyler1, University of Mississippi2
27 Mar 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: In this article, the authors explored the survival benefit of tofacitinib in addition to dexamethasone in hospitalized patients treated for coronavirus disease 2019 (COVID-19)-related pneumonia.

35 citations

Journal Article•10.1016/J.MAYOCPIQO.2020.08.005•
Development of a Novel Clinical Decision Support System for Exercise Prescription Among Patients With Multiple Cardiovascular Disease Risk Factors.

[...]

Linda S. Pescatello1, Yin Wu1, Gregory A. Panza1, Amanda L. Zaleski1, Amanda L. Zaleski2, Margaux A. Guidry •
University of Connecticut1, Hartford Hospital2
01 Feb 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: The support system P3-EX has proven to be an easy-to-use, guided, and time-efficient evidence-based approach to ExRx for patients with multiple CVD risk factors that has applicability to other chronic diseases and health conditions.

32 citations

Journal Article•10.1016/J.MAYOCPIQO.2021.08.011•
Association between accelerometer-assessed physical activity and severity of COVID-19 in UK Biobank.

[...]

Alex V. Rowlands1, Alex V. Rowlands2, Paddy C. Dempsey, Clare L Gillies1, David E Kloecker3, David E Kloecker1, Cameron Razieh1, Cameron Razieh2, Yogini Chudasama1, Nazrul Islam4, Francesco Zaccardi1, Claire A. Lawson1, Tom Norris1, Melanie J. Davies1, Melanie J. Davies2, Kamlesh Khunti1, Thomas Yates2, Thomas Yates1 •
Leicester General Hospital1, University Hospitals of Leicester NHS Trust2, St George's, University of London3, University of Oxford4
20 Aug 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: In this article, the authors quantify the association between accelerometer-assessed physical activity and coronavirus disease 2019 (COVID-19) outcomes and find that a greater proportion of vigorous activity was associated with lower odds of severe and nonsevere infections.

28 citations

Journal Article•10.1016/J.MAYOCPIQO.2021.03.009•
Risk Factors for Premature Myocardial Infarction: A Systematic Review and Meta-analysis of 77 Studies.

[...]

Sagar B Dugani1, Sagar B Dugani2, Yousif M Hydoub, Ana Patricia Ayala3, Roger Reka3, Tarek Nayfeh1, Jingyi Francess Ding1, Shannon N McCafferty4, Muayad A Alzuabi1, Medhat Farwati1, M. Hassan Murad1, Alawi A. Alsheikh-Ali5, Samia Mora2 •
Mayo Clinic1, Brigham and Women's Hospital2, University of Toronto3, University of Pittsburgh4, University of Medicine and Health Sciences5
23 Jun 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: In this article, the authors evaluated the magnitude of the association between risk factors and premature myocardial infarction (MI) (men aged 18-55 years; women aged 18 to 65 years).

25 citations

Journal Article•10.1016/J.MAYOCPIQO.2020.09.014•
Empowering the Clinical Research Coordinator in Academic Medical Centers

[...]

Danielle A. Buchanan1, Jody Goldstein2, Anna C Pfalzer1, Ya-Chen Lin1, Hakmook Kang1, Daniel O. Claassen1 •
Vanderbilt University Medical Center1, University of Rochester2
01 Apr 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: Surprisingly, greater workload and lack of opportunity for professional growth were not associated with retention and the CRCs who feel respected and engaged by the PI and are adequately compensated are more likely to have higher job satisfaction and retention.

22 citations

Journal Article•10.1016/J.MAYOCPIQO.2021.01.003•
Perceptions of Barriers and Facilitators to Becoming a Medical Professional Among Underrepresented Undergraduate and Postbaccalaureate Learners

[...]

Josiane Joseph1, Dyda Dao1, Soyun Michelle Hwang2, Steven M. Dotzler1, Sherry S. Chesak1, Taylor M. Weiskittel1, Margaret E. Lang1, Valeria Melo1, Jacob B. Anderson1, Beatriz Vega1, Mckenzie Englund3, Paige M. Boruch3, Paige M. Boruch1, Anjali Bhagra1 •
Mayo Clinic1, Johns Hopkins University2, University of Minnesota3
01 Apr 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: In this article, a qualitative study with focus groups was designed to assess underrepresented undergraduate and post-baccalaureate learners' perceptions of the medical field, barriers that might prevent individuals from pursuing professional medical careers, and resources that assist in overcoming these barriers.
Journal Article•10.1016/J.MAYOCPIQO.2021.05.007•
Non-invasive Vocal Biomarker is Associated with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection.

[...]

Elad Maor1, Nir Tsur2, Galia Barkai1, Galia Barkai2, Ido Meister3, Shmuel Makmel3, Eli Friedman3, Daniel Aronovich, Dana Mevorach, Amir Lerman4, Eyal Zimlichman2, Eyal Zimlichman1, Gideon Bachar2 •
Sheba Medical Center1, Tel Aviv University2, United Kingdom Ministry of Defence3, University of Rochester4
14 May 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: Voice analysis is associated with SARS-CoV-2 status and holds the potential to improve the accuracy of self-reported symptom-based screening tools, according to a pilot study suggesting a possible role for vocal biomarkers in screening for Sars-CoVs infected subjects.
Journal Article•10.1016/J.MAYOCPIQO.2020.09.011•
Assessment of Common Comorbidity Phenotypes Among Older Adults With Knee Osteoarthritis to Inform Integrated Care Models.

[...]

Trevor A. Lentz1, Anne S. Hellkamp1, Nrupen A. Bhavsar1, Adam P. Goode1, Ajay Manhapra2, Ajay Manhapra3, Ajay Manhapra4, Steven Z. George1 •
Duke University1, Veterans Health Administration2, Eastern Virginia Medical School3, Yale University4
19 Jan 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: It is suggested that existing clinical pathways that rely on single or dominant providers might be insufficient for a large proportion of older adults with KOA, and development of integrated KOA-comorbidity care pathways that are responsive to emerging priorities for personalized, value-based health care.
Journal Article•10.1016/J.MAYOCPIQO.2020.12.005•
Robotics in Simulated COVID-19 Patient Room for Health Care Worker Effector Tasks: Preliminary, Feasibility Experiments a .

[...]

W. David Freeman1, Devang Sanghavi1, Masood S. Sarab1, Mary S. Kindred1, Elizabeth M. Dieck1, Suzanne M. Brown1, Tom Szambelan, Justin Doty, Brendan Ball, Heidi M. Felix1, Jesse C. Dove1, Jorge M. Mallea1, Christy Soares2, Leslie V. Simon1 •
Mayo Clinic1, Florida State University2
01 Feb 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: A collaborative robot system could perform health care worker effector tasks inside a simulated intensive care unit (ICU) patient room, which could theoretically reduce both PPE use and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposures.
Journal Article•10.1016/J.MAYOCPIQO.2020.12.004•
Digital Health Surveillance Strategies for Management of Coronavirus Disease 2019.

[...]

Thulasee Jose1, David O. Warner1, John C. O’Horo1, Steve G. Peters1, Rajeev Chaudhry1, Matthew J. Binnicker1, Charles D. Burger1 •
Mayo Clinic1
01 Feb 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: The key to harnessing the potential of digital surveillance tools to promote patient-centered care during COVID-19 pandemic was to use the registry data, reports and dashboards as informatics tools to inform decision-making.
Journal Article•10.1016/J.MAYOCPIQO.2020.12.006•
Use of Post-Acute Care Services and Readmissions After Acute Myocardial Infarction Complicated by Cardiac Arrest and Cardiogenic Shock.

[...]

Saraschandra Vallabhajosyula1, Stephanie Payne1, Jacob C. Jentzer1, Lindsey R. Sangaralingham1, Kianoush Kashani1, Nilay Shah1, Abhiram Prasad1, Shannon M. Dunlay1 •
Mayo Clinic1
08 Feb 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: CA is associated with increased post–acute care use, whereas CS is associatedWith increased readmission risk in AMI survivors, and there were no differences for emergency department visits.
Journal Article•10.1016/J.MAYOCPIQO.2020.10.007•
Clinical Characteristics and Risk Factors for Death of Hospitalized Patients With COVID-19 in a Community Hospital: A Retrospective Cohort Study.

[...]

Guillermo Rodriguez-Nava1, Maria Adriana Yanez-Bello1, Daniela Patricia Trelles-Garcia1, Chul Won Chung1, Sana Chaudry1, Aimen S. Khan1, Harvey J. Friedman1, Harvey J. Friedman2, David W. Hines1 •
Saint Francis University1, University of Illinois at Chicago2
01 Feb 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: Older patients, LTCF residents, and patients with high qSOFA scores were found to have worse clinical outcomes and increased risk of death in this single-center retrospective cohort study in Cook County, Illinois.
Journal Article•10.1016/J.MAYOCPIQO.2021.11.002•
The Impact of the COVID-19 Pandemic on OB/GYN Providers

[...]

Kirsten A. Riggan1, Jensen Reckhow1, Megan Allyse1, Margaret E. Long1, Vanessa E. Torbenson1, Enid Y. Rivera-Chiauzzi1 •
Mayo Clinic1
10 Nov 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: The impact of the COVID-19 pandemic on OB/GYN providers is assessed in this article, where the authors report that the pandemic had a negative professional impact on their relationships with patients and colleagues.
Journal Article•10.1016/J.MAYOCPIQO.2021.08.002•
Lung function and symptoms in post-COVID-19 patients: a single-center experience.

[...]

Nicola Mumoli, Aldo Bonaventura, Alessandra Colombo, Alessandra Vecchié, Marco Cei, Josè Vitale, Luca Pavan, Antonino Mazzone, Francesco Dentali 
10 Aug 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: While inflammatory biomarker levels normalized after 3 months, signs of lung damage persist for a longer period, and support the need for implementing post-CO VID-19 outpatient clinics to closely follow-up COVID-19 patients after hospitalization.
Journal Article•10.1016/J.MAYOCPIQO.2020.08.013•
Changing Drivers of Mortality Among Patients Referred for Cardiac Stress Testing.

[...]

Alan Rozanski1, Alan Rozanski2, Heidi Gransar2, Sean W. Hayes2, John D. Friedman2, Louise Thomson2, Daniel S. Berman2 •
Icahn School of Medicine at Mount Sinai1, Cedars-Sinai Medical Center2
03 May 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: A marked contemporary shift in the drivers of all-cause mortality among patients undergoing cardiac stress tests among patients referred for radionuclide stress testing is suggested, away from such factors as typical angina and inducible myocardial ischemia, which are declining in prevalence, and toward such factor as diabetes and an inability to perform exercise, which is increasing in prevalence.
Journal Article•10.1016/J.MAYOCPIQO.2020.10.001•
Cardiovascular and Renal Outcomes Associated With Hyperkalemia in Chronic Kidney Disease: A Hospital-Based Cohort Study.

[...]

Shun Kohsaka1, Suguru Okami2, Eiichiro Kanda3, Naoki Kashihara3, Toshitaka Yajima2 •
Keio University1, AstraZeneca2, Kawasaki Medical School3
19 Jan 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: Hyperkalemia was associated with significant risks for mortality and adverse clinical outcomes, with more rapid decline of renal function, and the significance of hyperkalemic as a predisposition to future adverse events in patients with chronic kidney disease is underscore.
Journal Article•10.1016/J.MAYOCPIQO.2021.06.011•
Role of Geographic Risk Factors in COVID-19 Epidemiology: Longitudinal Geospatial Analysis.

[...]

Young J. Juhn1, Philip H. Wheeler1, Chung-Il Wi1, Joshua T. Bublitz1, Euijung Ryu1, Elizabeth H Ristagno1, Christi A. Patten1 •
Mayo Clinic1
12 Jul 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: In this article, the authors performed a geospatial and temporal trend analysis for coronavirus disease 2019 (COVID-19) in a Midwest community to identify and characterize hot spots for COVID-2019.
Journal Article•10.1016/J.MAYOCPIQO.2021.01.007•
The use of electrocardiogram screening to clear athletes for return to sport following COVID-19 infection.

[...]

Jacob L. Erickson1, Joseph T. Poterucha1, Alecia Gende1, Mark McEleney1, Corey M. Wencl1, Marisa Castaneda1, Lindsay Gran1, Joel Luedke2, Jill Collum3, Karen M. Fischer1, Andrew R. Jagim1 •
Mayo Clinic1, University of Wisconsin–La Crosse2, University of Saint Mary3
08 Feb 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: In this article, the occurrence rate of abnormal ECG findings and symptoms following COVID-19 infection was quantified to quantify the occurrence of abnormal EKG and symptoms in adults who were participating in collegiate athletics.
Journal Article•10.1016/J.MAYOCPIQO.2021.01.013•
Naltrexone Initiation in the Inpatient Setting for Alcohol Use Disorder: A Systematic Review of Clinical Outcomes.

[...]

Robert Kirchoff1, Norhan M. Mohammed1, Jack McHugh1, Matej Markota1, Thomas Kingsley1, Jonathan G. Leung1, M. Caroline Burton1, Rahul Chaudhary1 •
Mayo Clinic1
01 Apr 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: In this article, the authors summarize the data on naltrexone initiation in the emergency department or inpatient setting for the management of alcohol use disorder (AUD) in the United States.
Journal Article•10.1016/J.MAYOCPIQO.2021.08.009•
Resilience, Well-being, and Empathy Among Private Practice Physicians and Advanced Practice Providers in Texas: A Structural Equation Model Study.

[...]

Anthony C. Waddimba1, Anthony C. Waddimba2, Monica Bennett2, Michelle Fresnedo1, Michelle Fresnedo2, Thomas G. Ledbetter2, Ann Marie Warren1, Ann Marie Warren2 •
Baylor University Medical Center1, Scott & White Hospital2
17 Sep 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
Journal Article•10.1016/J.MAYOCPIQO.2020.09.009•
Endoscopic Lung Volume Reduction: Review of the EMPROVE and LIBERATE trials

[...]

Khaled M. Nada1, Shawn P.E. Nishi1•
University of Texas Medical Branch1
01 Feb 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: This article provides an overview of the two largest prospective trials performed with the FDA-approved valve systems and no clear benefit of one over the other is found.
Journal Article•10.1016/J.MAYOCPIQO.2021.01.011•
Premature Myocardial Infarction: A Community Study

[...]

Sagar B Dugani1, Matteo Fabbri1, Matteo Fabbri2, Alanna M. Chamberlain1, Suzette J. Bielinski1, Susan A. Weston1, Sheila M. Manemann1, Ruoxiang Jiang1, Véronique L. Roger1 •
Mayo Clinic1, Albert Einstein College of Medicine2
01 Apr 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: In this article, the authors evaluated the trends in incident premature myocardial infarction (MI) and prevalence of cardiac risk factors in a population-based cohort and found that the risk factor profile of persons presenting with MI worsened over time, especially in men.
Journal Article•10.1016/J.MAYOCPIQO.2021.03.002•
EVALI: A Mimicker of COVID-19.

[...]

Mitchell M. Pitlick1, Daenielle K. Lang1, Anne M. Meehan1, Christopher P. McCoy1•
Mayo Clinic1
29 Mar 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: In the current pandemic, diagnosis of EVALI may be delayed because of anchoring bias when patients present with symptoms consistent with coronavirus disease 2019 (COVID-19) as mentioned in this paper.
Journal Article•10.1016/J.MAYOCPIQO.2021.09.008•
Mortality Correlates in Patients With Takotsubo Syndrome During the COVID-19 Pandemic.

[...]

Amanda Chang1, Yi Grace Wang2, Manju B. Jayanna3, Xiaodong Wu1, Linda Cadaret1, Kan Liu1 •
University of Iowa1, California State University, Dominguez Hills2, Lankenau Medical Center3
29 Sep 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: In this article, a systematic review of Takotsubo syndrome (TTS) cases reported during the coronavirus disease 2019 (COVID-19) pandemic and performed clustering and feature importance analysis and statistical testing for independence on the demographic, clinical and imaging parameters.
Journal Article•10.1016/J.MAYOCPIQO.2020.12.007•
Painful Subacute Thyroiditis is Commonly Misdiagnosed as Suspicious Thyroid Nodular Disease

[...]

Josephine H. Li1, Gilbert H. Daniels1, Giuseppe Barbesino1•
Harvard University1
03 Feb 2021-Mayo Clinic Proceedings: Innovations, Quality & Outcomes
TL;DR: Painful subacute thyroiditis demonstrates specific sonographic patterns that may be misdiagnosed as suspicious thyroid nodular disease and recognition of the innocent and transient nature of these findings is important for the proper management and monitoring of these patients.
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