TL;DR: It is postulate that FGF, IGF-1, and EGF are important mitogens for wound healing and that EGF in particular is capable of stimulating epithelialization.
TL;DR: A randomized cross-over study between CO2 and nitrogen gases to test the hypothesis that the CO2 absorbed during laparoscopy, rather than the 15 mmHg intra-abdominal pressure created, accounted for changes in acid-base and hemodynamic changes during pneumoperitoneum.
TL;DR: Both tPA and uPA may be used to prevent adhesion formation when delivered locally in a rat uterine horn devascularization and serosal injury model in a blinded, randomized study.
TL;DR: The effect of IFN-gamma on cell proliferation, collagen production, and expression of types I and III procollagen mRNA in human postburn H TS fibroblasts was at least as pronounced in HTS fibro Blasts as their normal controls.
TL;DR: BAL therapy prolonged survival and improved both laboratory and clinical markers of fatal liver failure, indicating that this BAL may have clinical utility in supporting human liver failure.
TL;DR: The experimental data suggest that the two new lipid substances, SL and GL, are the most likely candidates for routine clinical use in the prevention of postsurgical adhesions.
TL;DR: Apart from autoclaved PDBM, all matrix grafts showed excellent new bone formation after sterilization, exceeding the results of allogenic cancellous bone.
TL;DR: This study examined the effect of IL-6 alone and in combination with TNF-alpha on three neutrophil functions--CD18 adhesion receptor expression, phagocytosis, and superoxide anion generation.
TL;DR: It is suggested that gut peptides mediate the initiation and maintenance of postoperative small bowel ileus in rats by preoperative administration of VIP and SP receptor antagonists, (VIP-ra and SP-ra).
TL;DR: Comparison of Northern and Western blotting results revealed a dichotomy in the ratio of relative GS mRNA and protein level in rat organs, suggesting that tissue-specific posttranscriptional processes determine GS protein levels.
TL;DR: The shortage of lung donors for clinical transplantation could be significantly alleviated if lungs could be retrieved from cadavers hours after death, but this was markedly attenuated in O2-ventilated cadaveric rat lung.
TL;DR: No appears to have a biphasic effect on DNA synthesis in passaged RFPASM, with stimulation at micromolar concentrations and inhibition at higher levels, and may alter vascular smooth muscle growth and pulmonary vascular remodeling in conditions complicated by pulmonary hypertension and treated with inhaled NO.
TL;DR: TNF-α, a proinflammatory cytokine, appears to be a good biological marker for postoperative intraabdominal adhesion formation and may be a correlation between higher levels of tumor necrosis factor-α and higher rates ofAdhesion formation following standard bowel injury.
TL;DR: The affinity of rifampin to bond to Dacron permits implantation of a vascular prosthesis with anti-staphylococcal bioactivity and a bonding technique with optimal graft bioactivity was developed which was then used for in situ reconstruction of a biofilm graft infection.
TL;DR: In this article, the influence of peritoneal macrophage enhancement on postoperative adhesion formation in five groups of rabbits was studied, and it was concluded that enhancement of peri-itoneal Macrophages by protease peptone reduced markedly the degree of post-operative adhesive formation.
TL;DR: The magnitude of reperfusion-induced intestinal mucosal damage in a standardized rat model of complete segmental arterial ischemia as a function of the occlusion time may be very significant in early forms of complete occlusions of the mesenteric circulation.
TL;DR: It is suggested that HA is useful to evaluate the extent of endothelial cell damage after cold storage and reperfusion, and the significance of HA as a predictor of graft viability is confirmed.
TL;DR: It is postulated that administration of a novel construct of two modified soluble p55 receptors linked to polyethylene glycol (PEG-BP-30) would also attenuate the hemodynamic and hematologic alterations to lethal Escherichia coli septic shock in non-human primates.
TL;DR: Northern blot hybridization demonstrates, for the first time, the specific kinetics of cytokine gene expression in the liver, spleen, lung, and kidney after PH.
TL;DR: Findings suggest that systemic intervention therapy of burn patients with DHEA or a similar acting steroid hormone may be useful in preventing the progressive tissue destruction caused by progressive ischemia.
TL;DR: The results demonstrate that liver allografts may be efficiently transfected with adenovirus expressing viral IL-10 and offer the promise of effectively and favorably altering the alloreactive immune response.
TL;DR: Treatment with high volume intraperitoneal SCMC prevents reformation of adhesions following surgical lysis, and this effect is demonstrated by a proportionate and significant decrease in the incidence of intraabdominal adhesion associated with administration of increasing amounts of SCMC.
TL;DR: The results suggested that patients with septic complications following esophagectomy had alterations of monocyte phenotype and function, which may contribute to the understanding of the complicated mechanism involved in surgical stress and the development of postoperative sepsis.
TL;DR: L-arginine supplementation resulted in the preservation of acetylcholine-mediated relaxation but did not change hypercholesterolemia-induced contractile agonist supersensitivity.
TL;DR: Differences in expression of cell surface activation markers on circulating leukocytes and systemic, soluble, serum cytokine levels between healthy controls and patients with CVSU were determined.
TL;DR: Computer-generated tumor volume determination is reproducible, accurate, and easily obtained from hard copy scans and provides a quantitative in vivo measurement for use as a prognostic or therapeutic response variable.
TL;DR: To determine the origin, cell type present, and rate of endothelial cell coverage of PTFE grafts, 5-cm segments of 4-mm-diameter, 60-microns PTFe grafts were implanted end-to-end bilaterally in the carotid arteries of greyhound dogs.
TL;DR: Whether glutamine-supplemented total parenteral nutrition (TPN) enhanced DNA and protein synthesis in the liver and whether glutamine uptake was increased following partial hepatectomy in rats was determined.