TL;DR: The increased likelihood of infection attending primary closure of contaminated wounds with percutaneous sutures gives strong support to the thesis that per cutaneous suture should be avoided in the closure of contaminated wounds.

TL;DR: Fracture healing is retarded in rats with uncontrolled alloxan diabetes, as determined by tensile-strength and histochemical evaluation of the fracture callus.

TL;DR: A technique for orthotopic liver homotransplantation in the pig is presented, describing the method of obtaining blood for transfusion; the anesthetic technique, with special reference to endotracheal intubation; and the preparation of the donor liver.

TL;DR: Threshold of cardiac response to endocardial stimulation has been determined as a function of electrode surface area and it has been that electrodes should be matched to the pulse generator output capacity and that an excessively large electrode will yield high acute thresholds and chronic thresholds above the output capacity of some pacemakers.

TL;DR: Porcine renal xenografts were prolonged ten to twenty times longer than controls by specific suppression of the dog's antipig erythrocyte antibody by techniques involving either multiple Xenografting or intravenous administration of pig stroma.

TL;DR: The effectiveness of neutralizing the pH of intravenous fluids in reducing the histological evidence of phlebitis was shown in a control study using both hind legs of 16 dogs.

TL;DR: Pluronic F68 (a nonionic surface-active agent) has been shown to decrease the vascular resistance in a series of 10 pig spleens perfused with human blood and to increase the duration of successful perfusion from 1 to 6 hours.

TL;DR: Experimental wound infections were produced in all instances with a standard number of organisms, without generalized toxicity, and the incidence of infection in S. aureus -contaminated wounds was decreased following antibiotic irrigation but was not statistically significant.

TL;DR: The maintenance of a slight rise of femoral arterial pressure and the fall of central venous pressure which occurred after blood loss in these studies results in an influx of fluid into the bloodstream, which support the classic Starling hypothesis of fluid replacement after hemorrhage.

TL;DR: Study of the healing of standard tibial fractures in rats treated with hyperbaric oxygen revealed that although callus formation was increased the breaking strength was reduced as compared to atmospheric controls.

TL;DR: The investigation of the intrahepatic distribution of hepatic arterial flow in the isolated perfused canine liver showed that a part of it is shunted into the portal venous system before the sinusoidal level, which suggests the presence of a unidirectional arterioportal shunt, which may explain the mechanism by which arterial blood controls portals venous flow.

TL;DR: No rise in minimal surface tension was observed in animals placed on controlled ventilation without cardiopulmonary by pass; only one of 6 animals with thoracotomy and heparin showed a persistent rise.

TL;DR: In this paper, the influence of castration, timing, testosterone proprionate treatment, pilocarpine administration, and other combinations of these factors were studied in a total of 34 dogs, 2 rhesus monkeys, and 10 men.

TL;DR: A reasonably standardized and reproducible method which reduces many variables, so that a truer estimate can be made of the histopathological, physiological, and pharmacological changes effected by cigarette smoking than heretofore has been provided.

TL;DR: Following end-to-side portacaval shunt in the rat with a normal liver, there is a significant increase in enzymatic activity of histidase and histidine-pyruvate transaminase, but no significant change in urocanase activity is noted.

TL;DR: A new method to arrest the cerebral circulation of a dog is described, in which the major intraspinal arteries surrounding the cervical spinal cord are divided or thrombosed in a preliminary operation.

TL;DR: It has been demonstrated that the constituent cells of a noninterpositional canine hip arthroplasty surface have adequate potential to produce the necessary matrix components, but the present experimental model is not suited for the more desirable study of a longer time.

TL;DR: Homotransplantation of the liver necessarily entails variable periods of hepatic anoxia, but this problem may be partially obviated by diversion of the accumulated blood in the newly vascularized transplanted liver for a protracted period of time before recirculation in the recipient is permitted.

TL;DR: It is suggested that during the process of incubation small amounts of RNA or DNA enter the graft cells and there induce synthesis of “foreign” antigen which replaces or competes with the original antigen.

TL;DR: Data on trapped plasma using the microhematocrit technique on “normal” canine blood at various packed cell volumes are presented and a series of three trapped plasma factors is suggested for blood volume determinations in canine research.

TL;DR: Changes in cytoplasmic organelles of the mouse ascites sarcoma BP8 (C3H tumor) were studied histochemically during enhanced growth in C57 B1 mice, consistent with an antibody-mediated damage to the oxidative cellular processes duringEnhanced growth of the BP8 tumor.

TL;DR: Analysis of functional extracellular fluid volume changes and sodium balance indicated that fluids given by these extravascular routes are comparable in their effects to the same solutions given intravenously.

TL;DR: The completed study of the variation of PT in serum in pancreatitis using the chromogenic peptide, GGANA, as a substrate will be reported later.

TL;DR: Aortic pressure and coronary flow were found at low normal levels in the adrenalectomized animal but were significantly increased after cortisol administration, and oxygen consumption and carbon dioxide production similarly rose after cortisol along with the increased cardiac work.