Showing papers in "Heliyon in 2022"
TL;DR: Liposomes are now considered the most commonly used nanocarriers for various potentially active hydrophobic and hydrophilic molecules due to their high biocompatibility, biodegradability, and low immunogenicity.
Abstract: Liposomes are now considered the most commonly used nanocarriers for various potentially active hydrophobic and hydrophilic molecules due to their high biocompatibility, biodegradability, and low immunogenicity. Liposomes also proved to enhance drug solubility and controlled distribution, as well as their capacity for surface modifications for targeted, prolonged, and sustained release. Based on the composition, liposomes can be considered to have evolved from conventional, long-circulating, targeted, and immune-liposomes to stimuli-responsive and actively targeted liposomes. Many liposomal-based drug delivery systems are currently clinically approved to treat several diseases, such as cancer, fungal and viral infections; more liposomes have reached advanced phases in clinical trials. This review describes liposomes structure, composition, preparation methods, and clinical applications.
618 citations
TL;DR: In this article , the authors discuss the relationship between the modification in CSNPs as multifunctional delivery systems and drug release properties and kinetics of the drug release model, and conclude that almost all CSNs showed bi-phasic release, initial burst release drug in a particular time followed controlled manner release in achieving the expected release, stimuli external can be applied.
258 citations
TL;DR: In this article , the authors provide an insight into the potential of various biomass as an energy source and discuss the technical, socio-economic and environmental concerns and limitations with the appropriate control measures.
231 citations
TL;DR: A thorough review of state-of-the-art and classical strategies for PID controller parameters tuning using metaheuristic algorithms can be found in this article , where the primary objectives of PID control parameters are to achieve minimal overshoot in steady state response and lesser settling time.
227 citations
TL;DR: In this paper , an inexpensive biosorbent that is successfully utilized in removing methyl orange and methylene blue dyes from wastewater was successfully synthesized and activated using phosphoric acid, and the results of the scanning electron microscope and N2 adsorption/desorption examination affirmed that the prepared nanocomposite is permeable.
222 citations
TL;DR: In this article , a systematic literature review explores digital financial inclusion across countries, and finds that developing countries, mainly Asian countries, embrace and improve Digital financial inclusion to help reduce poverty, but a persistent divide exists between gender, the wealthy and the poor, and urban and rural areas regarding access to and usage of digital financial services.
214 citations
TL;DR: In this article , a very promising renewable resource including its potential uses in paper, textiles, composites, biofuel, and food industry is reviewed, with the focus on renewable resources along with the search for alternatives to carbon-positive materials.
162 citations
TL;DR: In this paper , the authors reviewed and discussed the different types of additive manufacturing techniques and the properties and challenges associated with additively manufactured titanium-based alloys and found that 3D printed titanium and titanium-alloys exhibit huge prospects for various applications in the medical and aerospace industries.
142 citations
TL;DR: In this paper , an approach to removing crystal violet (CV) dye from aqueous solutions was investigated by introducing a xanthate group on charred rice husk and Xanthated Rice husk.
139 citations
TL;DR: In this article , the effect of organizational citizenship behavior and transformational leadership on small and medium-sized enterprises (SMEs) performance was investigated using a sample of 405 employees from Pakistani SMEs, in terms of engaging them in voluntary work that ultimately improves performance.
128 citations
TL;DR: Probiotics are a colony of bacteria that live in our intestines and are regarded as a metabolic 'organ' due to their beneficial effects on human health, including metabolism and immunological function as discussed by the authors .
TL;DR: In this article , date seeds were used as active adsorbents to remove methyl violet (MV) dye from the aqueous solutions in the model experiments, and two isotherm models, Langmuir and Freundlich, were studied to fit the equilibrium data.
TL;DR: In this article , a survey of 1074 valid samples revealed that habits and attitudes are crucial factors in the success of basketball learning using a metaverse, while grade and gender are moderator variables.
TL;DR: In this article , the authors investigated the effectiveness of the flex model of blended learning in teaching the mathematics subtopic of coordinates in the plane through the improvement of students' academic achievement, self-study skills and learning attitudes.
TL;DR: In this paper , the authors used a fresh panel technique known as cross-sectionally augmented autoregressive distributive lag (CS-ARDL) to estimate the impact of industrialization, urbanization, electrification, and industrialization on the environment of five industrialized economies (Brazil, Russia, India, China, and South Africa).
TL;DR: In this article , a comprehensive review of e-learning in higher education institutions (HEIs) during the COVID-19 pandemic is presented, which comprises citation analysis, co-citation analysis, and co-occurrence of keyword analysis.
TL;DR: In this paper , the authors assessed the perception and preference for e-teaching among 438 faculty members and found that around half of teachers were conducting e-classes without any training, and they also had conducted examinations using online platforms.
TL;DR: In this article , a review of Islamic FinTech research development from 2017 to 2022 is presented, which adopts a hybrid approach combining bibliometric and content analysis to reveal the current research trend of Islamic fintech research.
TL;DR: In this article , the physicochemical and biopharmaceutical aspects encountered in the pathway of drugs through the skin, and the potential added value of using solid lipid nanoparticles (SLN) and nanostructured lipid vectors (NLC) to drug permeation/penetration through this route.
TL;DR: Stinging nettle (Urtica dioica L) is a wild herbaceous perennial blooming plant that is commonly known as stinging nettle as discussed by the authors , which is a plant that's edible and has nutritional and medicinal properties.
TL;DR: In this article , a review of the structure and regulatory functions of P-glycoprotein, as well as the crucial role it plays in health and disease, is presented, where the authors reveal that the binding sites within P-Glycoprotein can accommodate a variety of compounds with diverse structures.
TL;DR: In this article , a review of the proper preparation of enzymes laccase, lignin peroxidase, and manganese peroxideidase is presented, as well as the important factors influencing their activity.
TL;DR: In this article , a review discusses bacterial isolates that have been used successfully to degrade and decolourise textile dyes, their mode of dye removal as well as the factors that affect their dye degradation ability.
TL;DR: The surface area of most activated carbon from lignocellulosic biomass by H3PO4 was in the variability of 456.1-2806 m2/g, yielding 26.1 -85 % and an extreme adsorption capacity of 2.5-89.29 mg/g as mentioned in this paper .
TL;DR: In this article , the authors reviewed the conversion of agricultural wastes into bio-fuels with special emphasis on bioethanol, biohydrogen, biobutanol, biomethane, biometric, and biodiesel for various applications and concluded that wastes generated from agricultural activities and processes are useful and can be harnessed to meet the affordable and accessible global renewable energy target.
TL;DR: In this article , the authors have stirred the pool of relevant literature to extract some of the innovative efforts that have been deployed into redirecting the potential of plastic waste into useful applications like engineering and building construction, horticulture in agriculture, and the most advanced application is the 3D printing using plastics as filaments.
TL;DR: In this article , the authors present a bibliometric analysis of research trends in the application of solid-state fermentation in the bioprocessing of agro-industrial wastes.
TL;DR: In this article , the potentiality of Sb-chalcogenides such as antimony selenide (Sb2Se3) and Sb2S3 as absorber material in HJSCs with 2D tungsten disulfide (WS2) electron transport layer (ETL) layer has been investigated numerically using SCAPS-1D solar simulator.
TL;DR: In this article , a detailed bibliometric analysis of keywords, terms and timelines in the research field of the flood research has been performed, by examining the research frontiers from 2000 to 2021.
TL;DR: In this paper , a Systematic Literature Review (SLR) is presented to identify the different antecedents prevailing in the literature on elderly technology adoption, and a conceptual framework for elderly's technology adoption and recommendations are presented.