TL;DR: This study is the first comprehensive analysis of the anatomy and developmental regulation of the divergently evolved and axially regionalized peptidergic nervous system in Hydra, implicating an ancestral origin of neural regionalization.
TL;DR: It is shown that TUBB3 is expressed in the developing neural plate, is upregulated in the pre-migratory cranial neural crest prior to cell delamination and migration, and it is maintained or up regulated in neurons in later developmental stages.
TL;DR: The identification and a detailed spatio-temporal expression profile of sirtuin genes in the short-lived fish Nothobranchius furzeri, from embryogenesis to late adulthood, mapping its entire life cycle is reported, providing the foundation for future research, both into genetic and pharmacological manipulation of this important group of enzymes.
TL;DR: A detailed comparative analysis of trio and kalrn expression in Xenopus laevis development is shown, providing first insights into their redundant or distinct functions in a vertebrate model system.
TL;DR: Three epididymis-specific SPINKs (serine protease inhibitors, Kazal-type): SPINK8, SPINK11, and SPINK12 are characterized and it is found that these epididcyal SPinks are expressed in an epididykal region-specific manner and their expression is developmentally regulated.
TL;DR: The results identified a different set of reference genes under each experimental setup such as electron transfer flavoprotein-ubiquinone oxidoreductase, ubiquitin, UBIQ and glyceraldehyde 3-phosphate dehydrogenase (GAPDH) as best reference genes in adult whitefly.
TL;DR: The dynamic expression patterns of MDK, PTN and their receptors suggest that they function together during the multistep process of ocular development and they may play important roles in cell proliferation, adhesion, and migration of neuronal and non-neuronal cells.
TL;DR: Detailed immunostaining in the developing cerebellum is performed, with particular focus on GCPs and GCs, looking at several transcription factors, signaling molecules, cell cycle regulators, some of which are known to regulate neural development, to provide a basis for future studies on the cerebellar GC development and medulloblastoma.
TL;DR: Cloning of zebrafish ankef1a, as well as its paralog, ankef 1b, and expression analyses by whole-mount in situ hybridization and quantitative polymerase chain reaction (qPCR) during embryonic development and in adult tissues suggest an important role for ANKEF1 in ciliated tissues and during embryonicDevelopment.
TL;DR: By comparative in situ hybridization analysis, many Shh and non-canonical Wnt signaling-related molecules showed spatiotemporal expression patterns during palatal rugae development, including restricted expression in the epithelium (placode and interplacodes) and mesenchyme.
TL;DR: It is confirmed that progenitor cells of condylar cartilage are rapidly differentiated into hypertrophic chondrocytes, which is a unique structural feature of secondary cartilage different from that of primary cartilage, and suggested that MMPs and/or TIMPs are more actively involved in the development of Condylar (secondary) cartilage than tibial (primary) Cartilage.
TL;DR: This study characterize Rbfox1l and Rb fox2 expression in the adult zebrafish brain and finds that Rb Fox1l is expressed in restricted populations of neurons in the dorsal telencephalon and cerebellum.
TL;DR: A functional screen using the UAS/Gal4 system was performed to identify non-coding cis-regulatory elements within well-characterized ecdysone-response genes capable of driving transcription of an indelible reporter in ovarian cells, providing novel insight into the molecular regulation of ecDysone signaling in oogenesis.
TL;DR: Real-Time PCR was employed to evaluate the temporal and spatial expression patterns of some floral organ identity genes in the inflorescence and different floret organs in the two stages of green and purple florets of bolting garlic clone, finding that these genes seem to be influential in the formation of floral organs in bolts garlic.
TL;DR: During neural tube formation, axis elongation, and organogenesis, RECK, TIMP-2, and MT1-MMP proteins show highly similar localization patterns, particularly in the ectoderm and in the dorsal-ventral differentiation of the neural tube.
TL;DR: Results support the notion that Sox9 promotes cell migration activities needed for prostate ductal elongation, as well as identifying 702 sex-dependent and 95 Sox9-dependent genes, some of which also function in cell migration.
TL;DR: Epigenetics erasure is required for resetting the cell identity to a ground state during the production of induced pluripotent stem (iPS) cells from somatic cells and the existence of subtle differences in the imprinting loci between different types of iPS cells and embryonic stem (ES) cells is highlighted.
TL;DR: Results suggested that three Elmo family members share their functional roles in various brain regions during prenatal-postnatal development, including those of the cerebrum, hippocampus, and cerebellum.
TL;DR: It is found that Sjfz7 encodes a 698 amino acid protein with typical characteristics of Frizzled proteins that might be associated with the development of musculature, intestinal tract and reproductive organs in schistosome and comparing frizzled mRNA levels between not fully developed and normal worms suggested that Wnt signaling might be abnormal inNot fully developed worms.
TL;DR: It is demonstrated that PP2A2, PUB3 and EF1-α are the most stably expressed genes across the tested conditions and therefore appropriate for RT-qPCR.
TL;DR: It is shown that zebrafish prkacs are expressed throughout the developing nervous system, each showing unique expression patterns, which will inform future functional studies into the roles of PKA during development.
TL;DR: The developmental expression patterns of these two fosl genes is different in Xenopus embryos, and real-time quantitative PCR results showed that the expression of the two genes was increased from stage 2 to stage 42, however, expression level of fosL1 is much higher than that offosl2 at stage 42.
TL;DR: Analysis of the WormBase transcripts provides a framework for investigating interactions between the novel ECP-1, EXC-2 and some other proteins, including IFs, which show a similar excretory canal phenotype and are essential for development of the C. elegansexcretory cells.
TL;DR: expression profiles of some of the important innate and adaptive immune genes during ontogenetic developmental stages and in different tissues of catla were investigated using quantitative real-time PCR and revealed that immune genes IL-1β, C3, IgM and IgZ were detected in the unfertilized eggs indicating their maternal inheritance.
TL;DR: It is shown in a condensed species tree that the existence of unc119 genes correlates with the presence of cilia across eukaryotes and that phylogenetic evidence suggests there are three subgroups of UNC119 proteins.
TL;DR: In situ hybridization results showed that KMT2d mRNA is expressed in the developing calvarial osteoblasts, epithelia and neural tissues, suggesting that Kmt2d plays an intrinsic role in normal development and homeostasis of these craniofacial tissues.