TL;DR: Specific antibodies were raised against Sycp3, Plzf and Cyclin B3 in zebrafish and then used to determine the localization of these proteins in the testis, showing that these molecules have properties that will enable their use as markers of spermatocytes and early sperMatogonia inZebrafish.
TL;DR: A systematic analysis to identify "optimal" HK genes in Danio rerio (zebrafish) to be used in expression analyses conducted on embryos/larvae at different developmental stages, as well as on differentiated adult tissues from single donors showed that beta-actin 2 (bactin2) is the mRNA with the lowest variability of expression.
TL;DR: The expression of four clock genes during tooth development is investigated, suggesting that clock genes might be involved in the regulation of ameloblast and odontoblast functions, such as enamel and dentin protein secretion and matrix mineralization.
TL;DR: Evidence is provided that the adult Drosophila midgut arises from a molecularly distinct population of single cells present by the embryonic/larval transition, and the identification of the Ecdysone receptor as a regulator of AMP expansion.
TL;DR: The domain organization and expression of the entire, core neurexin superfamily in the nematode Caenorhabditis elegans is described and it is found that nrx-1 is exclusively expressed in most if not all cells of the nervous system and localizes to presynaptic specializations.
TL;DR: The HMGB family in zebrafish is characterized and a detailed phylogenetic analysis of HMGB proteins is reported, highlighting substantial overlaps, but also subtle differences and specificities in the expression patterns of the zebra fish hmgb genes.
TL;DR: Evidence of Unfolded Protein Response (UPR) activation during normal lens development and differentiation in the mouse is found and a role for UPR activation in lens fiber cell differentiation during embryogenesis is proposed.
TL;DR: The findings suggest that the loss of regenerative capacity of the adult organ of Corti is related to down-regulation of stem/progenitor key-markers from the mature supporting cells.
TL;DR: The cloned two zebrafish lgr genes are cloned and showed that these two genes are orthologs of mammalian Lgr4 and Lgr6, providing a basis for future studies aimed at analyzing the functions of zebra fish Lgr 4 and L gr6 in cell differentiation and proliferation during organ development.
TL;DR: It is shown that Crip2 is highly expression in the myocardium, moderately expressed in the endocardium and absent from the epicardium of the developing mouse heart, implying that Crips2 might exert an important impact on the cardiovascular development, maintenance and homeostasis.
TL;DR: Findings suggest that in addition to its previously suggested roles in testis or sperm, Ci-VSP plays a key role in voltage-induced signal transduction in cells of the digestive system and blood.
TL;DR: Comparison with the expression patterns of the different vertebrate orthologues indicates a conserved role of those genes in posterior mesoderm formation in chordates.
TL;DR: The results indicate that CRTC1 protein is expressed in SMG epithelia during early stages of morphogenesis, disappears with differentiation, and reappears in initial tumor-like pathology, suggesting thatCRTC1 may play a role during embryonic SMG branching morphogenesis but not for pro-acinar/acinar differentiation, supporting a precursor cell origin for MEC tumorigenesis.
TL;DR: It is shown that dPlod is required for type-IV collagen secretion from haemocytes and fat body, and thus it is established that LH3 enzyme function is conserved across widely separated animal phyla.
TL;DR: Wnt7 genes are mainly expressed in a number of CNS structures at developmental stages at which patterning and neural specification takes place, which suggests diverse as well as redundant involvements during brain development.
TL;DR: Stage- and tissue-specific expression in different muscle types for Zasp52 isoforms encoding different LIM domains are demonstrated, implying muscle-specific functions in Z-disk assembly or maintenance.
TL;DR: Cloned a ric-8 gene from Xenopus tropicalis (xtric-8) and determined its spatiotemporal expression pattern throughout embryogenesis suggest that RIC-8 functions are related to the development of the nervous system.
TL;DR: Limitation of S100-like gene expression to chondrocytes of cartilaginous tissues undergoing endo/perichondral mineralization in juvenile fish further confirmed the mineralogenic role of the protein in fish and emphasized the potential of S 100-like as a marker of mineralizing cartilage in developing fish.
TL;DR: Both dkk3 genes display a unique and distinct expression pattern in late embryonic development, pointing to a specific role during neuronal and pancreatic cell differentiation.
TL;DR: Results suggest that Fgf signalling is active in the pancreatic mesenchyme, where expression of Spred1/2 and Spry2/4 appear downstream of F gf9 signalling.
TL;DR: Seven genes involved in metabolism, catabolism and binding of RA are described during organogenesis in the clawed frog Xenopus laevis, indicating regions of the embryo that could be affected by RA mediated patterning and identifies some differences with other vertebrates.
TL;DR: It is found that Sizn1 is primarily restricted to the ventral forebrain including the medial ganglionic eminence, the septum, amygdala, and striatum, and its expression is detected in the cortical hem and pallial-subpallial boundary (PSB; anti-hem); both sources of Cajal-Retzius cells.
TL;DR: This detailed study of the spatial and temporal expression of LimK1 shows that LIMK1 expression is more dynamic than previously reported, in particular at sites of tissue-tissue interactions guiding multiple developmental processes.
TL;DR: It is demonstrated that postembryonic sim, instead, controls aspects of axon guidance in the brain and resembles the roles of vertebrate sim that have an early role in neuronal migration and a later role in axonogenesis.
TL;DR: It is speculated that disturbance in the expression of the Atp7a gene and, consequently, change in the copper concentration of the organs, may contribute to the early fatal outcome of mosaic males.
TL;DR: Results indicate that Ednra expression may be linked with non-epithelial fate determination and differentiation of metanephric mesenchyme and may serve as a useful tool in studies on renal function and pathophysiology of various renal diseases.
TL;DR: In this article, a zebrafish ortholog of the human collagen XV gene, Col15a1a, was identified and its complete primary sequence was identified, showing that the overall structure of collagen XV is well conserved between vertebrates.
TL;DR: Eppk1 serves as a useful marker for detecting the hepatic progenitor population in the developing and adult liver and the use of EppK1 as a marker will facilitate studies of mouse hepatic PROGenitor cells.