TL;DR: In situ hybridization and immunostaining on histological sections of mouse testes revealed a strikingly specific and dynamic change of cellular specificity in the germ line during the progression of spermatogenesis, suggesting that genes in this subclass are not simply redundant.

TL;DR: Two orthologues of the mammalian gene Runx2a and runx2b are identified, which share sequence homology and gene structure with the mammalian genes, and map to regions of the zebrafish genome displaying conserved synteny with the region where the human gene is localized.

TL;DR: It is found that Foxc2 is expressed in lymphatic primordia, jugular lymph sacs, lymphatic collectors and capillaries, as well as in podocytes, developing eyelids and other tissues associated with abnormalities in lymphedema-distichiasis syndrome.

TL;DR: The mouse expression patterns of the three known members of the novel RGM gene family ('Repulsive Axonal Guidance molecules' A, B and C) are characterized by in situ hybridization for the first time.

TL;DR: Examination of the expression of Dlk in oval cells in the rat 2-acetylaminofluorene/partial hepatectomy (2AAF/PH) model demonstrates thatDlk is expressed in a subpopulation of oval cells and that DlK(+) cells represent intermediate cells between Dllk(-) oval Cells and mature hepatocytes.

TL;DR: Fascin-1 was widely expressed throughout the embryo and the developing nervous system and mesenchymal tissues represented major sites of expression.

TL;DR: Analysis of expression patterns of three zebrafish ER genes during development using whole-mount in situ hybridization found that high levels of esr2a and esR2b of maternal origin are inherited and segregated to the blastomers, while slight labeling is observed for esr1 transcripts.

TL;DR: It is shown that both of the Zic genes are expressed prior to and throughout gastrulation, and expression of Zic3 correlates well with the first steps in the establishment of the left-right axis.

TL;DR: This study shows that multiple Wnt and Dkk genes are expressed during lens development, predominantly in the epithelial compartment but is also associated, particularly in the case of Wnt7b, with early events in fibre differentiation.

TL;DR: The normal development of eyes relies on proper signaling through Fibroblast growth factor (FGF) receptors, but the source and identity of cognate ligands have remained largely unknown, and it is found that Fgf19 is expressed in the developing chicken retina.

TL;DR: A complete comparative analysis of maf gene expression patterns in vertebrates is presented and it is reported that the developing lens, kidney, pancreas and apoptotic zones of limb buds show sustained co-expression of large maf genes.

TL;DR: The results suggest that the Notch pathway may be active during mouse preimplantation development, particularly between the inner cell mass and the trophectoderm of the blastocyst.

TL;DR: Real time PCR is an efficient and powerful tool for studying multiple gene expression patterns during gonad development and differentiation, and can provide insight into gene interactions.

TL;DR: The expression patterns of these four zebrafish neuropilin genes in wild type embryos from the beginning of somitogenesis to 48 h post-fertilization are characterized.

TL;DR: Using in situ hybridization, it is shown that LHX3 and LHX4 are expressed in the developing human pituitary and along the rostro-caudal length of the spinal cord; here, both transcripts are detected in the ventral part giving rise to motorneurons and interneurONS.

TL;DR: Lhx2 is specifically expressed in the liver-associated septum transversum mesenchyme that subsequently becomes an integral part of the liver and the formation of these mesenchymal cells does not require functional LhX2.

TL;DR: The analysis confirmed the previously described pre-meiotic or meiotic expression for several genes, in particular for those involved in the regulation of the mitotic and meiotic cell cycle, and for those whose transcripts are accumulated during the meiotic stages to be translated later in post-meiotics stages.

TL;DR: The identification of zebrafish vangl1 is described and the first spatiotemporal expression and functional analysis of a vertebrate vang l1 homologue is provided, suggesting that Vangl 1 and Trilobite/Vangl2 have similar biochemical activities during embryogenesis.

TL;DR: These results provide the first developmental description of GnRH gene expression where cGnRH-II and sGn RH are initially expressed at the onset of the first day after fertilization.

TL;DR: The genome of the fruitfly Drosophila melanogaster encodes a single ortholog of the majority of the mammalian DGC protein subclasses, thus potentially simplifying their functional analysis and finding that they are predominantly expressed in the nervous system and in muscle.

TL;DR: ES cells are validated as a developmentally dynamic model for mechanistic investigations into this regulatory network early in embryogenesis preceding organogenesis and immunohistochemical analysis of preimplantation embryos for Ahch and key partners confirmed in vivo expression of network components.

TL;DR: Two nrp1 and two n rp2 genes, with expression patterns similar to higher vertebrates, have been isolated from zebrafish and an alternatively-spliced transcript of the nrP1b gene is identified which is predicted to encode a soluble form of NRp1b, containing only the a, b, and c extracellular domains.

TL;DR: Whole-mount in situ hybridization showed that the zebrafish fabp7a transcripts were distributed in the early developing central nervous system and were also detected in the swim bladder and pharynx during the embryonic to larval transitory phase.

TL;DR: It is shown here that germ cells isolated during migration (at E10.5) will migrate actively to the genital ridges, whereas post-migratory PGCs isolated from E12.5 embryos are non-motile even when transferred into a permissive environment.

TL;DR: Analysis of its spatiotemporal expression in mouse embryos showed that Drapc1 is expressed during development of the extraembryonic structures, nervous system, vascular system and inner ear, and is expressed in the mesenchyme of several developing organs at sites of epithelio-mesenchymal interactions.

TL;DR: The tetrapod limb exhibits distinct dorsoventral joint, tendon, and muscle asymmetry and the LIM-homeodomain transcription factor, LMX1b, is required to achieve the dorsal character of these structures, but the mechanism by which Lmx1b orchestrates this asymmetrical development is unknown.

TL;DR: The isolation of zebrafish growth factor independent 1 is described and an analysis of its pattern of expression during early development is presented, finding that gfi1 is expressed in the developing epithalamus in the dorsal diencephalon where its transcription is restricted to the parapineal.

TL;DR: A detailed description of the Otx2, Gbx2, and Fgf8 gene expression patterns in the chick developing inner ear is presented, comparing them with the Bmp4 expression, a putative sensory-organ marker, to suggest that expression domain boundaries could be involved in the specification of presumptive sensory patches.

TL;DR: Four discrete DNA elements within the 1.6 kbp promoter fragment are shown by electrophoretic mobility shift assays (EMSA) to exhibit sequence specific interactions with proteins present in nuclear extracts from P19 EC cells induced to express Pax3 by treatment with retinoic acid.