TL;DR: It is concluded that peristaltic dysfunction occurs in a substantial minority of patients with peptic esophagitis and could contribute to increased esophageal exposure to refluxed acid material.
TL;DR: It is concluded that neither omeprazole nor ranitidine per se is likely to induce proliferation of enterochromaffinlike cells and that they are reversible.
TL;DR: Serum alpha-fetoprotein levels were generally low, rarely assisted in diagnosis, but tended to increase when the mass attained a diameter of greater than 3 cm; sudden acceleration in the rate of increase in alpha- Fetoprotein level often coincided with a change of ultrasonic pattern to the massive one.
TL;DR: Esophageal balloon distention may provide a nonpharmacologic provocative test for esophageAL chest pain; and the mechanism of chest pain in patients with noncardiac chest pain may be related to lower pain threshold to Balloon distention, which is independent of esophagal contractions.
TL;DR: Motility varied widely between and within individuals, and differences between normal patterns in the jejunum and ileum were particularly striking, suggesting levels of recordings must be defined accurately if putative abnormalities, of possible clinical significance, are to be interpreted correctly.
TL;DR: Indium 111-granulocyte scans are a rapid, accurate, noninvasive means of assessing both disease extent and severity of colonic involvement in inflammatory bowel disease.
TL;DR: Five cases of an adenomatous hyperplastic nodule or a similar lesion resected from a cirrhotic liver in which early malignant foci were seen as small nodule-in-nodule lesions seem to represent an early stage of hepatocarcinogenesis in humans.
TL;DR: Sixty patients with anginalike chest pain of noncardiac origin were studied to determine the diagnostic value of 24-h ambulatory esophageal pH and pressure monitoring and the results showed the esophagus to be the likely cause of the pain in 35% of the patients.
TL;DR: This study validates the endoscopic identification of a visible vessel in a gastric ulcer, and confirms that such identification has a high predictive value for the development of recurrent hemorrhage.
TL;DR: It is concluded that essential dyspepsia patients who present for investigation with symptoms are more likely to be persistently neurotic, anxious, and depressed than dyspepsy-free controls, and this is unrelated to the presence of symptoms, but the association may not be of major clinical significance.
TL;DR: It is suggested that the transverse colon, not the cecum and ascending colon, may be the primary site for fecal storage and may provide a useful tool for evaluating normal and abnormal large intestinal physiology.
TL;DR: It is concluded that endoscopic polypectomy is adequate therapy for colonic polyps containing invasive carcinoma, provided that the favorable histologic features are present.
TL;DR: The initial endoscopic findings are of prognostic value in reflux esophagitis and smoking did not influence recurrence, and low-dose maintenance treatment with ranitidine does not prevent relapse.
TL;DR: Results indicate that in patients with sludge the gallbladder is abnormal, showing mucus hypersecretion and glandular metaplasia, which leads to an increase in the mucus content of gallbladders bile, which in turn may result in nucleation of cholesterol crystals and may be regarded as the embryonic stage of gallstone disease.
TL;DR: It is suggested that young women with severe constipation have great difficulty initiating the coordinated set of events that constitute a normal defecation response.
TL;DR: The sensitivity of three breath tests was studied and the need for evaluation of a 13CO2 breath test having the same characteristics as the [14C]xylose test (avidly absorbed substrate having minimal contact with the colonic flora) for nonradioactive breath detection of bacterial overgrowth in children and reproductive-age women is suggested.
TL;DR: The hypothesis that mucus released in response to topical application of an irritant plays an important role in the repair of epithelial damage through the process of restitution is supported.
TL;DR: It is suggested that the rapidity and spatial pattern of esophagealdistention, rather than discrimination of the type of material causing the distention, determines whether or not UES relaxation occurs.
TL;DR: By discriminant analysis a prognostic index with these laboratory investigations provided a high percentage of accuracy according to the outcome at the 18th month, compared with the patients who remained in remission who had a clinical relapse during follow-up.
TL;DR: It is suggested that linear gastric erosions found in patients with large diaphragmatic hernia are due to trauma and can cause chronic blood loss anemia in hernia patients.
TL;DR: Gastrointestinal bleeding is the most frequent form of bleeding after epistaxis in patients with hereditary hemorrhagic telangiectasia, most frequently in the upper gastrointestinal tract and predominantly in the stomach and the duodenum, and the typical endoscopic finding was nodular angiomas that did not differ, with regard to form and size, from external telang iectases.
TL;DR: In humans, the proximal and distal duodenal mucosa secretes bicarbonate at rest; direct acidification of the proxinal duodenum stimulates bic carbonate output; direct acids of the distalduodenum stimulate biccarbonate output'; and a proximal-to-distal gradient in bicarlate secretion is observed.
TL;DR: The literature contains nine well-documented cases of acute hepatic failure related to sickle cell disease and the mechanism is unclear; however, as the necrosis is often not severe, a metabolic problem is suggested.
TL;DR: Patients with peripheral edema appear to be protected from these effects because of the preferential mobilization of edema and may safely undergo diuresis at a rapid rate (greater than 2 kg/day) until edema disappears.
TL;DR: The hypothesis that mucus released in response to topical application of an irritant plays an important role in the repair of epithelial damage through the process of restitution is supported.
TL;DR: Recurrent bleeding from peristomal varices was a major problem; 7 of 10 patients required repeated blood transfusions and there was no perirectal bleeding in 4 patients with primary sclerosing cholangitis who underwent proctocolectomy with an ileoanal anastomosis.
TL;DR: The results show that the lymphocyte subpopulations in the lamina propria differ from those in peripheral blood in having predominantly the phenotypes of helper-inducer and cytolytic T cells, whereas the phenotype of suppressor-Inducer cells and activated suppressor cells are less frequently observed.
TL;DR: It is indicated that patients with duodenal ulcer disease secrete excessive amounts of gastric acid during the day and night and throughout an entire 24-h period.