Duzce Universitesi Tip Fakültesi Dergisi 

Abstract: Natural disasters cause extensive damage to nature and impact on large numbers of people throughout the world. Recently, earthquakes have caused a large number of death, injured, missing, and displaced people. More than a million earthquakes occur worldwide every year, which equates to roughly two earthquakes per minute. Lung problems in earthquakes are one of the main causes of morbidity and mortality. Many pulmonary complications that occur after earthquakes are a direct result of the disaster itself. Pulmonary complications such as inhalation of dust and particulates from collapsed buildings in earthquakes, aspiration of water and pathogens due to tsunami after earthquakes, pulmonary thromboembolism, psychological effects caused by respiratory symptoms, infectious respiratory diseases and chest traumas such as pneumothorax, rib fracture, hemothorax, hemopneumothorax, diaphragmatic tear can develop after earthquakes. People in the earthquake area, search and rescue teams, and those involved in demolition and debris removal activities are at risk for asbestos exposure. The most effective solution against the lung effects of earthquakes is to take preventive and protective measures. It is very important for disaster preparedness and response teams to be aware of these problems. Respiratory problems that may arise in earthquakes were discussed in this review.

Abstract: Aim: Laparoscopic cholecystectomy (LC) has become the standard treatment method of cholelithiasis. The chronic cholecystitis and cholelithiasis are the most common pathologies seen in gallbladder disease, accompanying hyperplastic and dysplastic lesions. Methods: 568 laparoscopic cholecystectomy procedures performed between 2008-2013 were analyzed. Clinical details and histopathological data were retrieved from the records. The variety of morphological changes in the diseased gall bladder were correlated with the clinical findings. Chronic cholecystitis and cholelithiasis were put into two groups. A single sample when taken from each neck-corpus and fundus of the gallbladder in the first group, two samples were taken from each site and gallbladder was mapped and examined as a whole in the second group. Results: The sex distribution of the cases was 525 (92.4%) and 43 (7.6 %) male (F/M: 12.1). Median age was 45.5 ± 12.7 years (range: 18-82), median operative time was 60.2 minutes (range: 17-200). Indications for surgery, were chronic cholecystitis in 525 (92.4 %), acute cholecystitis in33 (4.4 %), and gallbladder polyps in 6 (1 %). Acalculous cholecystitis was present in 2 patient(% 0.35) who were operated. Most common pathology noted in our study was chronic cholecystitis seen in 442 cases (%74). Other benign lesions were cholesterosis in 36 (%6) and acute cholecystitis in 28 (%.4). Various other associated lesions and variants of cholecystitis were also encountered. A total of six malignant lesions of gallbladder were observed, which included six cases of incidental adenocarcinomas. By increasing the sample size in gallbladder we saw an increase in the rate of metaplasia (p=0,009), dysplasia (p=0,009), epithelial hyperplasia (p=0.003), and carsinoma (p=0.008) statistically. Conclusion: By increasing the sample size in gallbladder we saw an increase in the rate of metaplasia, dysplasia and carcinoma statistically.

Abstract: Background: This study was designed to investigate the effects of Urtica dioica on liver ischemia reperfusion injury in rats. Methods: Thirty male Wistar-albino rats were used in this experimental study. Animals were divided into three groups as sham operated (group 1), control (group 2), and Urtica dioica treatment group (group 3). Urtica dioica 2ml/kg were administered intraperitoneally before ischemia and immediately after the reperfusion. The levels of total antioxidant capacity, total free sulfidril group, Total oxidant status, Oxidative stress index, and myeloperoxidase in liver tissues were measured. The serum levels of ALT, AST and LDH were also measured Results: Total antioxidant capacity and total free sulfidril group in liver tissue were significantly higher in group 3 than in group 2. Oxidative stress index and myeloperoxidase in liver tissue were significantly lower in group 3 than the group 2. The levels of liver enzymes in treatment group were significantly lower than those in the control group. Histological tissue damage was milder in the treatment group than that in the control group. Conclusion: It is concluded that Urtica dioica increase the antioxidant capacity and decrease oxidative stress and liver enzymes in the hepatic ischemi reperfusion injury of rats.

Abstract: Natural disasters, which are considered as one of the most important problems of recent times, affecting all humanity, have become a public health problem. Disasters have effects on both individuals and society in different dimensions, including health, economic, social, and psychological, and can have serious negative consequences. The number of individuals affected by natural disasters is increasing every year. While it is clear that natural disasters threaten human life and bodily health, little attention has been paid to their effects on mental health. Natural disasters threaten our psychological well-being in many ways, cause both short-term and long-term psychological distress and create a significant psychological burden. Post-traumatic stress disorder (PTSD) is a syndrome that occurs as a result of a serious threat or physical injury, a near-death experience, war-related trauma, sexual assault, interpersonal conflicts, child abuse, or a medical illness. When the literature is examined comprehensively, it has been determined that the incidence of PTSD after natural disasters is quite high. Causes of post-disaster PTSD include the nature of the trauma, its severity, loss of relatives and/or property, poor coping skills, displacement, and direct exposure to disaster. Studies have shown that both non-pharmacological and pharmacological treatments are effective on PTSD.