TL;DR: It is noted that cells of developing and mature human lenses as well as bovine lens cells in situ contain only beta- and gamma-actins, and extensive changes in actin-isoform expression take place in lens cells growing in culture and may also occur during cataractogenesis.
TL;DR: It is demonstrated that the regulation of keratinocyte growth and differentiation is mesenchyme-dependent; it is mediated by diffusible factors; but that differences between epidermis of different body sites are also controlled by intrinsic programs.
TL;DR: The results suggest that HMBA induces differentiation of NTERA-2 cl.D1 EC cells along a pathway distinct from the pathway(s) induced by retinoic acid and BUdR.
TL;DR: The immunocytochemical analysis of smooth muscle actin in the hybrid intestines, which had developed as intracoelomic grafts for 12 days, revealed that the skin fibroblastic cells had been induced by the intestinal epithelial cells to differentiate into smooth muscle cells.
TL;DR: A6 antigen may provide a useful tool for the study of neoexpression of human blood group antigens in liver tumors, and was localized, using light and electron microscopy, in biliary epithelial cells of all ducts including Hering canals.
TL;DR: A discrete pattern of regulation for both the ALP and alpha 2(I) genes during osteogenic differentiation, which may involve both transcriptional and posttranscriptional regulation is indicated.
TL;DR: The results suggest that the initiation of expression of this and other adipocyte-specific genes during adipose conversion is regulated by the relative composition of transcription factor AP-1.
TL;DR: Investigation of age-dependent changes in the amount of 5-methyldeoxycytidine (5mdC) that DNA of various mouse tissues contains during the late-fetal and postnatal periods, using high-performance liquid chromatography demonstrates the importance of the peri- andPostnatal periods in establishment of tissue-specificity in 5mdC content.
TL;DR: The major M- approximately 230,000 plaque protein, the "bullous pemphigoid" (BP) antigen is examined to use as a marker selective for certain subsets of epithelial cell types and epithelium-derived tumors in studies of fetal and tumor development, including differentiation diagnosis of carcinomas.
TL;DR: Vimentin is constantly expressed in myoepithelial cells in situ and in vitro, and expression of vimentin in luminal epithelial Cells in vitro is not a result of monolayer cultivation as such, but rather associated with the increased growth rate seen in culture.
TL;DR: The results suggest that ADA is subject to strong cell-specific developmental regulation during functional differentiation of certain foregut derivatives in mice.
TL;DR: Transplantation studies show that the appearance of ectopic heads is preceded by an early increase in the 'positional value' (P-value) or 'head activation potential' of the gastric column, which varies according to the number of cellular receptors for factors serving as intercellular signals.
TL;DR: It seems that retinoic acid acts directly on the conversion of profilaggrin into filaggrins rather than on the production of terminally differentiating cells capable of accumulating this protein.
TL;DR: Growth factors appear to work in concert for certain hair follicles responses and in opposition for others, and may play a role in different phases of hair follicle development that require cell replication and invasion into the deeper dermis.
TL;DR: This work examined the effects of several oncogenes on the immortalization and differentiation of primary cultures of rat skeletal muscle myoblasts and enabled the reproducible establishment of myogenic cell lines from very small populations of myoblast or single primary myogenic clones.
TL;DR: These myosin analyses provide no evidence for the existence of satellite cell diversity among three rat muscles of different fiber-type composition, at least not under the applied in vitro conditions.
TL;DR: How the expression of a simple epithelial keratin pair in glial cells of the goldfish optic nerve may be associated with this system's capacity for continuous growth and regeneration is discussed.
TL;DR: Examination by electron microscopy revealed that the epithelial cells formed a polarized cuboidal-columnar monolayer on the Matrigel surface, which was consistent with a well-differentiated cytoplasm.
TL;DR: The GRP78 promoter may be useful for the efficient expression of heterologous genes in undifferentiated and differentiated mouse embryonal cells and during early mouse development.
TL;DR: It is concluded that the progeny of adult myoblasts exhibit more desmin-expressing cells of this type than embryonicMyoblasts do, and these desmine-positive, myosin-negative myoblast are proliferating cells.
TL;DR: It appears that factors other than unsaturation of pairing sites or interference with pachytene X-chromosome inactivation have to be considered in the wild, as the reduced oocyte numbers in Rb heterozygous female can contribute to the retention of isolated populations in contact zones.
TL;DR: In Xenopus laevis larvae, nerve-dependence for hindlimb regeneration takes place proximodistally as the nerve fibers grow in the limb and it gradually undergoes a process of proxIModistal differentiation.
TL;DR: Morphological and ultrastructural studies show a neoepidermis resembling normal skin, and characterization has here shown high-quality epidermal differentiation.
TL;DR: It can be concluded that, while some seminomas seem to be devoid of IFs, most of them show varied differentiation patterns usually with epithelial features but occasionally also with components commonly regarded as characteristic of myogenic or neurogenic differentiation.
TL;DR: It is shown that an amine oxidase in the blastocyst oxidizes polyamines in blastocele fluid, generating hydrogen peroxide which causes programmed cell death of normal and malignant cells with trophectodermal potential.
TL;DR: RNA extracted from limbs of mouse embryos of different ages and from cultures of embryonic and fetal myogenic cells shows that the appearance of beta enolase transcripts temporally correlates with the formation of the second generation of muscle fibers and suggests that the developmental transition from alpha to beta enlase is linked to a developmental program which takes place in fetal but not in embryonic muscle.
TL;DR: All cis-elements necessary for the specific and efficient expression of a single type I CK gene, in the context of epithelial differentiation, can be located in the vicinity of the gene itself and that more-distant elements are not required.
TL;DR: There is a sequential transition in transcription and RNA accumulation from predominantly alpha-cardiac to predominantlyalpha-skeletal actin during subsequent myotube maturation, which reflects the pattern of expression found during development in vivo.
TL;DR: Observations show that the three adhesion molecules L1, N-CAM and J1/tenascin are expressed by distinct cell populations and may serve as cell-type-specific markers in pathologically altered intestinal tissue.
TL;DR: The postmeiotic expression of the preproacrosin gene during mouse spermatogenesis was studied and the proteolytic active site segments His, Asp and Ser are part of the heavy chain, as well as a proline-rich COOH-terminus, which is not present in any other serine proteinase studied so far.