TL;DR: The studies suggest this domain is the structural region responsible for the bacterial properties of lactoferrin, having effectiveness against various Gram-negative and Gram-positive bacteria at concentrations between 0.3 microM and 3.0 microM, depending on the target strain.

TL;DR: Osmotic gradient, for example, is sufficiently strong to push at least 0.5 mg of lipids per hour and cm2 through the skin permeability barrier in the region of stratum corneum, but does not contribute much to the lipid penetration into dermis.

TL;DR: The results of the analysis of hotspots of mutations support the idea that emergence of somatic mutation is significantly influenced by neighbouring base sequences and is supposed that this influence is an important feature of somatics hypermutagenesis.

TL;DR: The physical proper and physical proper behavior of PE and PE l i r~somes are studied, as well as the Divalent cation effect, which describes theivalent effect of pH in PE systems.

TL;DR: It is concluded that the repulsive barrier properties of lipid-grafted PEG polymer chains originate mainly from a steric pressure and that this simple polymer steric stabilization is the basis for the extended in vivo circulation times observed for polymer- grafted liposomes.

TL;DR: Prolonged circulation with PEG-PE is independent of cholesterol, degree of saturation in either the PC or the PE lipid anchor, lipid dose, or addition of other negatively charged lipids, phosphatidylglycerol or cholesterol sulfate.

TL;DR: The rate of esterification catalysed by an immobilised lipase suspended in an organic reaction mixture shows similar dependence on aw in reaction mixtures based on five different organic solvents ranging in polarity from pentan-3-one to hexane, and in a liquid reactant mixture.

TL;DR: This review summarizes the information available on the structure, function, biosynthesis, gene organization and pathobiochemistry of the known sphingolipid activator proteins and offers models for their mode of action and for the topology of lysosomal digestion of glycolipids.

TL;DR: Two lipoxygenase isoenzymes present in the embryo of germinating barley seed have been purified to homogeneity and characterized and the occurrence of two isoenZymes was confirmed by peptide analysis of the proteins.

TL;DR: Results presented in this paper strongly suggest that the bile salt-dependent lipase is the only pancreatic enzyme involved in lipid digestion in cod.

TL;DR: Tissues that turn-over slowly, such as skeletal muscle and heart, contained more delta mtDNA than more rapidly dividing tissues, suchas liver, in agreement with studies performed by others.

TL;DR: DSPC/CH/DSPE-PEG2000 LUVs remained in the circulation for over 24 h after injection and may be clinically useful for sustained release of an entrapped drug in the bloodstream and for drug accumulation in solid tumors.

TL;DR: It was concluded that xanthophylls possess the ability to act as chain-breaking antioxidants in the peroxidation of membraneous phospholipids and may, therefore, be helpful in resisting membraneous phosphate liposomes against oxidative damage in vivo.

TL;DR: Data suggest an important role for magnetic field exposure in altering cellular processes, and changes in transcript levels, assessed by slot-blot analysis, have been found to parallel the changes in gene transcription.

TL;DR: The review endeavours to give up-to-date information on the biogenesis and intracellular targeting of malate dehydrogenase isoenzymes as well as enzymes cooperating with them in the flow of metabolites of a given pathway and organelle.

TL;DR: It is suggested that, while together with superoxide anion radical, NO .

TL;DR: Changes in the secondary structure and aggregation of chymotrypsinogen were investigated by infrared differenceSpectroscopy in conjunction with temperature and pressure tuning IR spectroscopy; both the amide I' band and side chain bands were studied.

TL;DR: The results presented here highlight the risk of using halogenated alcohols, both as solvents for proteins and as a test of the intrinsic capacity of proteins and peptides to adopt helical secondary structures.

TL;DR: A novel rat liver protein was detected and isolated that seemed to be androgen-dependent and it was markedly expressed only in young and adult male rat livers, and the localization of SMP30 was restricted to liver and kidney among numerous organs tested.

TL;DR: The present data suggest that the hypolipemic effect of these compounds may, at least partly, be mediated via a common mechanism; impaired production of lipoprotein particles due to reduced synthesis and esterification of cholesterol together with enhanced oxidation of fatty acids in the liver.

TL;DR: Six murine monoclonal antibodies specific for b-pathway ganglio-series gangliosides were established by immunizing C3H/HeN mice with these purified gangLiosides adsorbed to Salmonella minnesota mutant R595 and determined the expression of these ganglioides, especially GD1b, GT1b and GQ1b on mouse, rat, and human leukemia cells.

TL;DR: The gene coding for an extracellular lipase of Bacillus subtilis 168 was cloned and found to be expressed in Escherichia coli and revealed a frameshift, due to the presence of an additional adenine in the N-terminal region, which caused the interruption of the open reading frame.

TL;DR: Comparison of the sequences of the homologous enzymes from Rh.