Zihui Li
University of Wisconsin-Madison
13 Papers
11 Citations
Zihui Li is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Chemistry & Proteome. The author has an hindex of 6, co-authored 13 publications. Previous affiliations of Zihui Li include Jilin University.
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Papers
On-Tissue Derivatization with Girard's Reagent P Enhances N-Glycan Signals for Formalin-Fixed Paraffin-Embedded Tissue Sections in MALDI Mass Spectrometry Imaging.
Hua Zhang,Xudong Shi,Nhu Q Vu,Gongyu Li,Zihui Li,Yatao Shi,Miyang Li,Bin Wang,Nathan V. Welham,Manish S. Patankar,Paul Weisman,Lingjun Li +11 more
TL;DR: An on-tissue chemical derivatization strategy based on positively charged hydrazine reagent (Girard’s reagent P) coupled with matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) was developed for analysis of N-glycans from FFPE treated tissue sections to better understand the pathogenesis of cancer related aberrant glycosylation.
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In Depth Quantification of Extracellular Matrix Proteins from Human Pancreas.
Fengfei Ma,Daniel M. Tremmel,Zihui Li,Christopher B. Lietz,Sara Dutton Sackett,Jon S. Odorico,Lingjun Li +6 more
TL;DR: This work characterized human pancreatic ECM composition before and after decellularization using isobaric dimethylated leucine (DiLeu) labeling for relative quantification of ECM proteins using a novel correction factor to eliminate the bias introduced during sample preparation.
Mass Spectrometry Imaging of N-Glycans from Formalin-Fixed Paraffin-Embedded Tissue Sections Using a Novel Subatmospheric Pressure Ionization Source.
Yatao Shi,Zihui Li,Mildred A. Felder,Qinying Yu,Xudong Shi,Yajing Peng,Qinjingwen Cao,Bin Wang,Luigi Puglielli,Manish S. Patankar,Lingjun Li +10 more
TL;DR: This study coupled a novel subatmospheric pressure (SubAP)/MALDI source with a Q Exactive HF hybrid quadrupole-orbitrap mass spectrometer for in-situ imaging of N-linked glycans from formalin-fixed paraffin-embedded (FFPE) tissue sections and demonstrated the utility of this new platform for N-glycan imaging analysis.
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Ascaris suum Informs Extrasynaptic Volume Transmission in Nematodes.
Louise E. Atkinson,Yang Liu,Fiona M. McKay,Elke Vandewyer,Charles Viau,Allister Irvine,Bruce A. Rosa,Zihui Li,Qingxiao Liang,Nikki J. Marks,Aaron G. Maule,Makedonka Mitreva,Isabel Beets,Lingjun Li,Angela Mousley +14 more
TL;DR: In this paper, the authors investigated nonsynaptic neuropeptide signaling in nematodes mediated by the body cavity fluid and found that the As-PCF peptidome contains a catalog of neuro peptides including FMRFamide-like peptides and neuro peptide-like proteins.
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Evaluation of Collagen Alterations in Early Precursor Lesions of High Grade Serous Ovarian Cancer by Second Harmonic Generation Microscopy and Mass Spectrometry.
Kristal L Gant,Alexander N. Jambor,Zihui Li,Eric C. Rentchler,Paul Weisman,Lingjun Li,Manish S. Patankar,Paul J. Campagnola +7 more
TL;DR: In this paper, the authors used Second Harmonic Generation (SHG) microscopy and machine learning to classify the changes in collagen fiber morphology occurring in serous tubal intraepithelial carcinoma (STIC) lesions that are concurrent with HGSOC.
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