Zihua Chen
Central South University
16 Papers
107 Citations
Zihua Chen is an academic researcher from Central South University. The author has contributed to research in topics: Cancer & Biology. The author has an hindex of 7, co-authored 7 publications.
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Papers
The effect of immune microenvironment on the progression and prognosis of colorectal cancer
Jinxiang Chen,Zihua Chen +1 more
TL;DR: In this paper, 108 colorectal tumor samples and their peritumoral tissues were collected for immunohistochemistry of infiltrating lymphocytes, and the results showed that the percentage of T-bet-positive cells was significantly decreased, while the percentages of IL-17-, FOXP3-, CD49b-, and LAG-3 positive cells were significantly increased in tumor tissues compared to that in peritUMoral tissues.
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Over-expression of EphA2 and EphrinA-1 in human gastric adenocarcinoma and its prognostic value for postoperative patients.
TL;DR: EphrinA-1 over-expression was significantly correlated with TNM stages and lymph node metastasis, while EphA2 expression was found to be an independent prognostic factor of postoperative gastric adenocarcinoma.
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Overexpression of EphA2 correlates with epithelial–mesenchymal transition-related proteins in gastric cancer and their prognostic importance for postoperative patients
Futao Hou,Weijie Yuan,Jin Huang,Liyuan Qian,Zhikang Chen,Jie Ge,Shaobin Wu,Jinxiang Chen,Jixu Wang,Zihua Chen +9 more
TL;DR: Findings indicate that the overexpression of EphA2 correlates with the loss of epithelial proteins and the appearance of mesenchymal proteins, and may play a role in epithelial–mesenchymic transition in gastric cancer.
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Expression of EphA2 and E-cadherin in Gastric Cancer: Correlated with Tumor Progression and Lymphogenous Metastasis
TL;DR: Either the over- expression of EphA2 or the down-expression of E-cadherin is correlated with cancer progression and lymphogenous metastasis in gastric cancer, suggesting that both of them may play an important role in tumor progression and metastasis.
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LncRNA PCAT19 induced by SP1 and acted as oncogene in gastric cancer competitively binding to miR429 and upregulating DHX9
TL;DR: The results demonstrate that lncRNA PCAT19 is induced by SP1 and acts as an oncogene in GC that competitively binds to miR429 and upregulates DHX9.