Zhongyang Zhang
Shanghai Jiao Tong University
6 Papers
Zhongyang Zhang is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Medicine & Receiver operating characteristic. The author has an hindex of 4, co-authored 4 publications.
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Papers
Molecular magnetic resonance imaging of activated hepatic stellate cells with ultrasmall superparamagnetic iron oxide targeting integrin αvβ3 for staging liver fibrosis in rat model
TL;DR: Molecular MRI of integrin αvβ3 expressed on activated HSCs by using RGD-USPIO may distinguish different liver fibrotic stages in CCl4 rat model and shows promising to noninvasively monitor the progression of the liver fibrosis and therapeutic response to antifibrotic treatment.
Correlation between conventional MR imaging combined with diffusion-weighted imaging and histopathologic findings in eyes primarily enucleated for advanced retinoblastoma: a retrospective study.
Yanfen Cui,Yanfen Cui,Ran Luo,Ruifen Wang,Huanhuan Liu,Caiyuan Zhang,Zhongyang Zhang,Dengbin Wang +7 more
TL;DR: Conventional MRI has some limitations in reliably predicting microscopic infiltration, with the diagnostic efficiency showing room for improvement, whereas ADC values correlated well with certain high-risk prognostic parameters for retinoblastoma.
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A Deep Learning Model Based on MRI and Clinical Factors Facilitates Noninvasive Evaluation of KRAS Mutation in Rectal Cancer
Huanhuan Liu,Hongkun Yin,Jinning Li,Xue Dong,Hui Zheng,Ting T Zhang,Qiufeng Yin,Zhongyang Zhang,Minda Lu,Huiling Zhang,Dengbin Wang +10 more
TL;DR: The proposed combined DL model incorporating T2WI and clinical factors may show good diagnostic performance and could potentially serve as a supplementary approach for noninvasively evaluating KRAS mutation in rectal cancer.
9
Noninvasive monitoring of early antiangiogenic therapy response in human nasopharyngeal carcinoma xenograft model using MRI with RGD-conjugated ultrasmall superparamagnetic iron oxide nanoparticles.
Yanfen Cui,Caiyuan Zhang,Ran Luo,Huanhuan Liu,Zhongyang Zhang,Tian-Yong Xu,Yong Zhang,Dengbin Wang +7 more
TL;DR: It is demonstrated that the magnetic resonance molecular nanoprobes, RGD-PAA-USPIOs, allow noninvasive in vivo imaging of tumor angiogenesis and assessment of the early response to antiangiogenic treatment in NPC xenograft model, favoring its potential clinical translation.
A self-unfolding proximity enabling device for oral delivery of macromolecules.
Mahdi Ghavami,Jesper Pedersen,Rolf Bech Kjeldsen,Aage Kristian Olsen Alstrup,Zhongyang Zhang,Vasiliki Koulianou,Johan Palmfeldt,Thomas Vorup-Jensen,Lasse Højlund Thamdrup,Anja Boisen +9 more
TL;DR: A new generation of medical devices called self-unfolding proximity enabling devices are developed, which makes it possible to orally deliver macromolecules without perforating the intestine, and can facilitate enhanced absorption of minimally invasive oral Macromolecule formulations.