Zhiwei Chen
Wenzhou Medical College
7 Papers
Zhiwei Chen is an academic researcher from Wenzhou Medical College. The author has contributed to research in topics: Cancer cell & Cancer. The author has an hindex of 3, co-authored 7 publications.
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Papers
Ambidextrous Approach To Disrupt Redox Balance in Tumor Cells with Increased ROS Production and Decreased GSH Synthesis for Cancer Therapy
Longfa Kou,Longfa Kou,Rui Sun,Shuyi Xiao,Ya-Wen Zheng,Zhiwei Chen,Aimin Cai,Hailun Zheng,Qing Yao,Vadivel Ganapathy,Ruijie Chen +10 more
TL;DR: Treatment of tumor cells with SASP/ZnO NPs in vitro and in vivo resulted in a synergistic disruptive effect on redox balance in tumor cells and induced cell death and decreased tumor growth.
82
Nanoparticle mediated codelivery of nifuratel and doxorubicin for synergistic anticancer therapy through STAT3 inhibition.
Hailun Zheng,Zhiwei Chen,Aimin Cai,Xinlu Lin,Xinyu Jiang,Bin Zhou,Jun Wang,Qing Yao,Ruijie Chen,Longfa Kou +9 more
TL;DR: Poly (lactic-co-glycolic acid) nanoparticles are developed to achieve the simultaneous codelivery of doxorubicin (DOX) and nifuratel (NIF, a novel STAT3 inhibitor) for enhanced cancer therapy to suggest that DNNPs represented a promising strategy against gastric cancer by inhibiting the STAT3 pathway and amplifying apoptosis.
27
Carbidopa suppresses prostate cancer via aryl hydrocarbon receptor-mediated ubiquitination and degradation of androgen receptor
Zhiwei Chen,Aimin Cai,Hailun Zheng,Huirong Huang,Rui Sun,Xiao Cui,Weijian Ye,Qing Yao,Ruijie Chen,Longfa Kou +9 more
- 13 May 2020
TL;DR: This study implicates Carbidopa for the first time in effective suppression of prostate cancer via a mechanism, involving AHR-mediated proteasomal degradation of AR.
Patent
Application of sulfasalazine iron complex to preparation of antitumor medicines
Kou Longfa,Ruijie Chen,Yao Qing,Rui Sun,Shuyi Xiao,Zhiwei Chen,Aimin Cai,Hailun Zheng +7 more
- 21 Jun 2019
TL;DR: In this paper, the application of a sulfasalazine iron complex to the preparation of antitumor medicines is described, which is a promising practical application prospect for the development of medical applications.
Patent
Preparation of pachymaran and poly-beta-hydroxybutyrate nanoparticles and application of nanoparticles in preparing anti-colon-cancer drugs
Kou Longfa,Ruijie Chen,Yao Qing,Shuyi Xiao,Rui Sun,Zhiwei Chen,Aimin Cai,Hailun Zheng +7 more
- 14 Jun 2019
TL;DR: In this paper, the preparation of pachymaran and poly-beta-hydroxybutyrate nanoparticles and application of the nanoparticles in preparing anti-colon cancer drugs were discussed.