Zhiji Luo
National Institutes of Health
5 Papers
17 Citations
Zhiji Luo is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Chemistry & Viral entry. The author has an hindex of 3, co-authored 4 publications.
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Papers
Heparan sulfate assists SARS-CoV-2 in cell entry and can be targeted by approved drugs in vitro
Qi Zhang,Catherine Z. Chen,Manju Swaroop,Miao Xu,Lihui Wang,Juhyung Lee,Amy Wang,Manisha Pradhan,Natalie Hagen,Lu Chen,Min Shen,Zhiji Luo,Xin Xu,Yue Xu,Wenwei Huang,Wei Zheng,Yihong Ye +16 more
TL;DR: HS is established as an attachment factor that assists SARS coronavirus cell entry and reveals drugs capable of targeting this important step in the viral life cycle.
Heparan sulfate assists SARS-CoV-2 in cell entry and can be targeted by approved drugs in vitro
Qi Zhang,Catherine Z. Chen,Manju Swaroop,Miao Xu,Lihui Wang,Juhyung Lee,Amy Wang,Manisha Pradhan,Natalie Hagen,Lu Chen,Min Shen,Zhiji Luo,Xin Xu,Yue Xu,Wenwei Huang,Wei Zheng,Yihong Ye +16 more
TL;DR: HS is established as an attachment factor that assists SARS coronavirus cell entry, and drugs capable of targeting this important step in the viral life cycle are revealed.
Targeting heparan sulfate proteoglycan-assisted endocytosis as a COVID-19 therapeutic option
Qi Zhang,Catherine Z. Chen,Manju Swaroop,Miao Xu,Lihui Wang,Juhyung Lee,Manisha Pradhan,Min Shen,Zhiji Luo,Yue Xu,Wenwei Huang,Wei Zheng,Yihong Ye +12 more
TL;DR: HSPGs are established as an assisting factor for ACE2 in endocytosis-mediated coronavirus entry and drugs that can be repurposed to target this important stage in the viral life cycle are identified.
High-Throughput Platform for Novel Reaction Discovery.
TL;DR: A miniaturizable purification method is reported that enables rapid, high-throughput isolation of quaternary ammonium-tagged products from reaction mixtures with excellent purity using inexpensive equipment that can be easily set up in a typical organic chemistry laboratory.
1
Patent
Quinoline compounds and their preparation and use as antimalarial agents
Wenwei Huang,Hao Li,Wei Zheng,Wei Sun,Xiuli Huang,Xiao Lu,Philip E. Sanderson,Xin Xu,Pranav Shah,Kim C. Williamson,Zhiji Luo,Gregory J. Tawa +11 more
- 05 Feb 2021
TL;DR: In this article, compounds of formula (I) were defined, and a method of preparing such compounds was presented, where R1, R2, R3, A, and B are as defined herein.