Zhenni Wei
Chinese Academy of Sciences
10 Papers
Zhenni Wei is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Chemistry & In vivo. The author has an hindex of 5, co-authored 7 publications. Previous affiliations of Zhenni Wei include University of Science and Technology of China & Southern Medical University.
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Papers
Small-sized gadolinium oxide based nanoparticles for high-efficiency theranostics of orthotopic glioblastoma.
Zheyu Shen,Ting Liu,Zhen Yang,Zijian Zhou,Wei Tang,Wenpei Fan,Yijing Liu,Jing Mu,Ling Li,Vladimir I. Bregadze,Swadhin K. Mandal,Anna A. Druzina,Zhenni Wei,Xiao-Zhong Qiu,Aiguo Wu,Xiaoyuan Chen +15 more
TL;DR: ES-GON-rBSA-LF-RGD2 exhibited high biocompatibility and can transport across the in vitro BBB model and the in vivo BBB of mice due to its small particle size and LF receptor mediated transcytosis.
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Manganese-Zeolitic Imidazolate Frameworks-90 with High Blood Circulation Stability for MRI-Guided Tumor Therapy
Zhenqi Jiang,Bo Yuan,Nianxiang Qiu,Yinjie Wang,Li Sun,Zhenni Wei,Yanyin Li,Jianjun Zheng,Yinhua Jin,Yong Li,Shiyu Du,Juan Li,Aiguo Wu +12 more
TL;DR: After Y1 receptor ligand modification, the Mn-ZIF-90 nanosystem exhibited high drug loading, better blood circulation stability, and dual breast cancer cell membrane and mitochondria targetability, further favoring specific microenvironment-triggered tumor therapy.
Intelligent Pore Switch of Hollow Mesoporous Organosilica Nanoparticles for High Contrast Magnetic Resonance Imaging and Tumor-Specific Chemotherapy.
Lin Huang,Jie Feng,Wenpei Fan,Wei Tang,Xiaoxiang Rong,Wangjun Liao,Zhenni Wei,Yikai Xu,Aiguo Wu,Xiaoyuan Chen,Zheyu Shen +10 more
TL;DR: In this article, the authors reported the smart use of core/shell Fe3O4/Gd2O3 (FG) hybrid nanoparticles as a gatekeeper to block the pores of hollow mesoporous organosilica nanoparticles, which can yield an unreported large loading content (up to 20.4%) of DOX.
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Pressure-induced amorphous zeolitic imidazole frameworks with reduced toxicity and increased tumor accumulation improves therapeutic efficacy In vivo.
Zhenqi Jiang,Yanying Li,Zhenni Wei,Bo Yuan,Yinjie Wang,Ozioma Udochukwu Akakuru,Yong Li,Juan Li,Aiguo Wu +8 more
TL;DR: An amorphous ZIF-8 with high loading of 5-Fu through pressure-induced amorphization with favorable biocompatibility and long blood circulation is expected to be a promising nano-system for efficacious cancer therapy in vivo.
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Self-assembled, biocompatible and biodegradable TEMPO-conjugated nanoparticles enable folate-targeted tumor magnetic resonance imaging
Ozioma Udochukwu Akakuru,M. Zubair Iqbal,M. Zubair Iqbal,Chuang Liu,Jie Xing,Zhenni Wei,Zhenqi Jiang,Q.F. Fang,Bo Yuan,Elvis Ikechukwu Nosike,Jianbi Xia,Yinhua Jin,Jianjun Zheng,Aiguo Wu +13 more
TL;DR: The design, synthesis, and characterization of a self-assembled metal-free CA which is based on an organic nitroxide radical compartmentalized in the biocompatible, biodegradable natural polymer, chitosan (CS), alongside folate targeting for in vivo tumor MRI is reported, which ameliorates the otherwise short in vivo lifetimes of typical organic radicals-based CAs.
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