Zhao W
University of Michigan
5 Papers
10 Citations
Zhao W is an academic researcher from University of Michigan. The author has contributed to research in topics: Population & Alternative splicing. The author has an hindex of 3, co-authored 5 publications. Previous affiliations of Zhao W include Life Sciences Institute.
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Papers
Novel DNA methylation signatures of tobacco smoking with trans-ethnic effects.
C. Christiansen,Juan E. Castillo-Fernandez,Arce Domingo-Relloso,Arce Domingo-Relloso,Arce Domingo-Relloso,Zhao W,J. S. El-Sayed Moustafa,P-C Tsai,P-C Tsai,P-C Tsai,Jane Maddock,Karin Haack,Shelley A. Cole,Sharon L.R. Kardia,M Molokhia,Matthew Suderman,Chris Power,Caroline L Relton,Caroline L Relton,Andrew Wong,D Kuh,Alissa Goodman,Kerrin S. Small,Jennifer A. Smith,Maria Tellez-Plaza,Ana Navas-Acien,George B. Ploubidis,Rebecca Hardy,Jordana T. Bell +28 more
TL;DR: In this paper, the authors explored novel blood methylation smoking signals on the Illumina MethylationEPIC BeadChip (EPIC) array, which also targets novel CpG-sites in enhancers.
isoTarget: A Genetic Method for Analyzing the Functional Diversity of Splicing Isoforms In Vivo.
TL;DR: It is demonstrated that the difference in subcellular localization, rather than biochemical properties, leads to the two isoforms’ functional differences, and it is shown that the sub cellular enrichment of functional partners results in a DLK/Wallenda-Dscam[TM2]-Dock signaling cascade in axons.
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isoTarget: a genetic method for analyzing the functional diversity of splicing isoforms in vivo
Hao Liu,Sarah Pizzano,Ruonan Li,Zhao W,Macy W. Veling,Yujia Hu,Limin Yang,Limin Yang,Bing Ye,Bing Ye +9 more
TL;DR: It is demonstrated that the difference in subcellular localization between Dscam[TM1] and [TM2], rather than any difference in biochemical properties, leads to the two isoforms’ differential contributions to dendrite and axon development.
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The mediating role of epigenetic clocks underlying educational inequalities in mortality: a multi-cohort study
Giovanni Fiorito,Giovanni Fiorito,Pedron S,Ochoa-Rosales C,Cathal McCrory,Silvia Polidoro,Yan Zhang,Pierre Antoine Dugué,Pierre Antoine Dugué,Pierre Antoine Dugué,Scott M. Ratliff,Zhao W,Gareth J. McKay,Giuseppe Costa,Solinas Mg,Kathleen Mullan Harris,Rosario Tumino,Sara Grioni,Fulvio Ricceri,Salvatore Panico,Hermann Brenner,Hermann Brenner,Lars Schwettmann,M. Waldenberger,Pamela R. Matias-Garcia,Annette Peters,Allison M. Hodge,Allison M. Hodge,Graham G. Giles,Graham G. Giles,Graham G. Giles,Lauren Schmitz,Morgan E. Levine,Jennifer A. Smith,Yongmei Liu,Frank Kee,Ian S. Young,Bernardette McGuinness,Amy Jayne McKnight,van Meurs J,Trudy Voortman,Rose Anne Kenny,Paolo Vineis,Cristian Carmeli +43 more
TL;DR: The authors assessed the mediating role of altered aging of immune cells functioning captured by DNA methylation changes in blood (known as epigenetic clocks) in educational associated all-cause mortality.
Heterogeneity in polygenic scores for common human traits
Erin B. Ware,Lauren Schmitz,Jessica D. Faul,Arianna M. Gard,Colter Mitchell,Jennifer A. Smith,Zhao W,David R. Weir,Sharon L.R. Kardia +8 more
TL;DR: For reproducibility through rigor and transparency, it is recommended that researchers include a PGS with all available SNPs as a reference, and provide substantial justification for using alternative methods.