Zeng Jiang
8 Papers
Zeng Jiang is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 1, co-authored 4 publications.
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Papers
[18F]BIBD-239: 18F-Labeled ER176, a Positron Emission Tomography Tracer Specific for the Translocator Protein.
Hualong Chen,Zeng Jiang,Xuebo Cheng,Wei Zheng,Yuli Sun,Ziyue Yu,Tingyu Yang,Lu Zhang,Jun Yan,Yajing Liu,Xunming Ji,Zeying Wu +11 more
TL;DR: Conclusively, [18F]BIBD-239, similar to ER176 with low polymorphism sensitivity, has simple labeling conditions, high labeling yield, high affinity, and high specificity for TSPO, and it is planned for further evaluation in higher species.
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Synthesis and In Vitro and In Vivo Evaluation of 18F-Labeled Positron Emission Tomography Tracers for Imaging Aβ Plaques.
Wei Zheng,Yong Huang,Hualong Chen,Zeng Jiang,Ziyue Yu,Tingyu Yang,Lu Zhang,Xuebo Cheng,Yajing Liu,Qi Liu,Xunming Ji,Zeying Wu +11 more
TL;DR: In this paper , a series of derivatives of florbetapir (AV45) containing different numbers and positions of N atoms were synthesized and evaluated for in vitro affinity and in vivo biodistribution.
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[18F]BIBD-181: A Novel Positron Emission Tomography Tracer Specific for Synaptic Vesicle Glycoprotein 2A.
Zeng Jiang,Xuebo Cheng,Hualong Chen,Wei Zheng,Yuli Sun,Ziyue Yu,Tingyu Yang,Lu Zhang,Di Fan,Zhihao Yang,Yajing Liu,Lin Ai,Zeying Wu +12 more
TL;DR: The synthesis of the novel radiotracer [18F]BIBD-181 is reported, which exhibits excellent properties and may be a reliable probe of quantities for SV2A-related disease diagnosis.
2
Design of Novel 18F-Labeled Amino Acid Tracers Using Sulfur 18F-Fluoride Exchange Click Chemistry
Yong Huang,Hualong Chen,Lu Zhang,Yi Xie,Chengze Li,Ziyue Yu,Zeng Jiang,Wei Zheng,Xuan Ge,Ying Liang,Zehui Wu +10 more
TL;DR: Novel 18F-labeled amino acid tracers designed using sulfur 18F-fluoride exchange click chemistry exhibit high tumor uptake and visualization with PET imaging.
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18F-Labeled PET Tracers Specific for Adenosine A2A Receptor: Design, Synthesis, and Biological Evaluation.
Tingyu Yang,Wei Zheng,Xuebo Cheng,Zeng Jiang,Ziyue Yu,Lu Zhang,Yi Xie,Lianjie Du,Xuan Ge,Jiahuai Zhang,Leilei Yuan,Yajing Liu,Zehui Wu +12 more
TL;DR: Novel 18F-labeled PET tracers specific for adenosine A2A receptor (A2AR) were designed, synthesized, and evaluated. The tracers exhibit high affinity for A2AR and can be specifically imaged in regions with high A2AR expression.
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