Zeliang Wei
Third Military Medical University
6 Papers
19 Citations
Zeliang Wei is an academic researcher from Third Military Medical University. The author has contributed to research in topics: DNA polymerase & DNA clamp. The author has an hindex of 2, co-authored 2 publications.
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Papers
Binding Affinities among DNA Helicase-Primase, DNA Polymerase, and Replication Intermediates in the Replisome of Bacteriophage T7
Huidong Zhang,Huidong Zhang,Yong Tang,Seung-Joo Lee,Zeliang Wei,Jia Cao,Charles C. Richardson +6 more
TL;DR: Results suggest that the replication loop is released as a result of the nick formed when the lagged-strand DNA polymerase encounters the previously synthesized Okazaki fragment, releasing lagging-Strand DNA and retaining DNA polymerases at the replication fork for the synthesis of next Okazaki fragments.
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Kinetic analysis of bypass of 7,8-dihydro-8-oxo-2'-deoxyguanosine by the catalytic core of yeast DNA polymerase η.
TL;DR: Kinetic analysis of 8-oxoG bypass by yeast DNA Pol ηcore provides further understanding of the mechanism of mutation at this oxidation lesion with yeast DNA polymerase η, suggesting that dCTP incorporation is slower than the dissociation of the polymerase from DNA.
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pH-triggered fluorescent probe for sensing of hypochlorite and viscosity in live cells and chronic wound diabetic mice
Li Chai,Yunzhu Li,Haihui Yang,Yujie Wang,Ridong Huang,Zeliang Wei,Zixuan Zhan +6 more
- 01 Oct 2023
TL;DR: A pH-triggered fluorescent probe (H-VH) is developed for simultaneous detection of viscosity and hypochlorite (ClO-) in live cells and chronic wound diabetic mice, providing a tool for visualizing the diabetic skin ulcer healing process.
16
Multimode evaluating the fluctuation of lipid droplets polarity in acute kidney injury and tumor models
TL;DR: Wang et al. as discussed by the authors presented a multimode two-photon aggregation-induced emission fluorescent probe (TP-LDs) for sensitively detecting the polarity changes in LDs.
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Biomolecules-mediated electrochemical signals of Cu2+: Y-DNA nanomachines enable homogeneous rapid one-step assay of lung cancer circulating tumor cells.
Chengyong Wu,Li Yan,Zixuan Zhan,Runlian Qu,Yue Wang,Xianghu Zeng,Haihui Yang,Pan Feng,Zeliang Wei,Piaopiao Chen +9 more
TL;DR: Results indicate that this straightforward and efficient pretreatment and rapid, highly sensitive electrochemical assay holds great promise for liquid biopsy-based tumor detection using CTCs.
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