Zeji Du
Mayo Clinic
18 Papers
15 Citations
Zeji Du is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Transplantation & Xenotransplantation. The author has an hindex of 9, co-authored 18 publications.
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Papers
Identification of new carbohydrate and membrane protein antigens in cardiac xenotransplantation.
Guerard W. Byrne,Paul G. Stalboerger,Zeji Du,Tessa R. Davis,Christopher G.A. McGregor,Christopher G.A. McGregor +5 more
TL;DR: Recovery of the porcine &bgr;1,4 N-acetylgalactosaminyl transferase 2 suggests that an antibody response to a SDa-like carbohydrate may represent a new carbohydrate moiety involved in xenotransplantation.
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Human CD55 expression blocks hyperacute rejection and restricts complement activation in Gal knockout cardiac xenografts.
Christopher G.A. McGregor,Davide Ricci,Naoto Miyagi,Paul G. Stalboerger,Zeji Du,Elise A. Oehler,Henry D. Tazelaar,Guerard W. Byrne,Guerard W. Byrne +8 more
TL;DR: It is suggested that non-Gal antibody-induced chronic endothelial cell activation coupled to possible hemostatic incompatibilities may be the primary stimulus for delayed xenograft rejection of GTKO hearts.
B4GALNT2 and xenotransplantation: A newly appreciated xenogeneic antigen.
Guerard W. Byrne,Guerard W. Byrne,Saadullah Ahmad-Villiers,Zeji Du,Christopher G.A. McGregor,Christopher G.A. McGregor +5 more
TL;DR: Elimination of this source of immunogenic pig antigen should minimize acute injury by preformed anti‐pig antibody and eliminate an induced clinical immune response to this newly appreciated xenotransplantation antigen.
108
Changes in cardiac gene expression after pig-to-primate orthotopic xenotransplantation.
Guerard W. Byrne,Guerard W. Byrne,Zeji Du,Zhifu Sun,Yan W. Asmann,Christopher G.A. McGregor,Christopher G.A. McGregor +6 more
TL;DR: Significant changes in cardiac gene expression after pig‐to‐primate orthotopic xenotransplantation in mice are observed and these changes are consistent with those seen in humans after similar transplants.
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Curative Ex Vivo Hepatocyte-Directed Gene Editing in a Mouse Model of Hereditary Tyrosinemia Type 1.
Caitlin J. VanLith,Rebekah M. Guthman,Clara T. Nicolas,Kari L. Allen,Zeji Du,Dong Jin Joo,Dong Jin Joo,Scott L. Nyberg,Joseph B. Lillegard,Joseph B. Lillegard,Raymond D. Hickey +10 more
TL;DR: This is the first report of ex vivo hepatocyte-directed gene repair using CRISPR/Cas9 to demonstrate curative therapy in an animal model of liver disease.