Zbyszek Otwinowski
University of Texas Southwestern Medical Center
127 Papers
575 Citations
Zbyszek Otwinowski is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Biology & Protein structure. The author has an hindex of 43, co-authored 115 publications. Previous affiliations of Zbyszek Otwinowski include University of Illinois at Chicago & University of Texas at Dallas.
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Papers
Real-space analysis of radiation-induced specific changes with independent component analysis.
TL;DR: This work lays a foundation for a better understanding of protein-specific radiation chemistries and provides a framework for analysing effects of specific radiation damage in crystallographic and cryo-EM experiments.
Methodology and applications of automatic electron-density map interpretation by six-dimensional rotational and translational search for molecular fragments.
TL;DR: The electron density for a search fragment and for the crystal is expanded in the space of spherical harmonics Bessel functions to locate fragments precisely over a wide range of resolutions for structure types from small organic molecules to proteins.
12
The Bear Giant-Skipper genome suggests genetic adaptations to living inside yucca roots
TL;DR: It is found that proteins involved in odorant and taste sensing as well as in oxidative reactions have diverged significantly in Megathymus as compared to Lerema, another Grass-Skipper, which may be related to the unusual life style of Giant-Skippers.
12
The crystallographic fast Fourier transform. I. p3 symmetry
TL;DR: An algorithm for computing the discrete Fourier transform of data with threefold symmetry axes is presented, which reduces the computational complexity of such a Fouriertransform by a factor of 3.
11
Using surface-bound rubidium ions for protein phasing
Sergey Korolev,Irina Dementieva,Ruslan Sanishvili,Wladek Minor,Zbyszek Otwinowski,Andrzej Joachimiak +5 more
TL;DR: X-ray anomalous scattering from rubidium ions bound to the protein surface was used for phasing of the crystal structure of the hsp60 apical domain from Thermus thermophilus and data show that bound rubium ions can be used to determine protein structures and to study the interaction of monovalent metal ions with proteins and other macromolecules.