Z. Chen
6 Papers
Z. Chen is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 2, co-authored 6 publications.
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Papers
Extremely potent monoclonal antibodies neutralize Omicron and other SARS-CoV-2 variants
Z. Chen,Feng Zhang,Yusuke Matsuoka,Yaroslav Tsybovsky,Kendra West,C. Santos,Lisa F. Boyd,H. Nguyen,Anna Pomerenke,Tyler Stephens,Adam S. Olia,Valeria De Giorgi,Michael R. Holbrook,Robin Gross,Elena Postnikova,Nicole L. Garza,R. Johnson,David Margulies,P.D. Kwong,Hadar Alter,Ursula J. Buchholz,Paolo Lusso,Pamela Farci +22 more
TL;DR: Combinatorial antibody phage-display libraries from convalescent COVID-19 patients are used to generate monoclonal antibodies against the receptor-binding domain of the SARS-CoV-2 spike protein with ultrapotent neutralizing activity, which has an unusual breadth of neutralization.
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Improving the prediction of influenza vaccine effectiveness by refined genetic distance measure
Lirong Cao,Jingzhi Lou,Q Li,Chris Kp Mok,Z. Chen,Renee W. Y. Chan,P. T. Cheung,Ka Chun Chong,Eng-Kiong Yeoh,Paul K.S. Chan,Benny Zee,Mo Wang +11 more
TL;DR: In this article, the authors investigated the relationship between vaccine effectiveness and genetic distance on antigenic sites (AS) and identified key amino acid sites related to vaccine protection against influenza A/H1N1pdm09 and H3N2.
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Rapid review of government issued documents relevant to mitigation of COVID-19 in the US food manufacturing and processing industry
TL;DR: The priority of COVID-19 mitigation in the food processing industry was to protect the health and safety of industry workers while maintaining food supply chain resilience to minimize disturbance in theFood market and avoid food crisis.
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Epidemiological analysis of the gender-age structure of hospitalized patients with COVID-19 and their mortality in 2020-2021.
Eugeny Voronin,Izabella Aleksandrovna Khrapunova,A. S. Pechenik,O A Kravtsova,Z. Chen,M.P. Kostinov,M.N. Loktionova,Irene V. Yakovleva,Vasilij G. Akimkin,V. Brazhnik +9 more
TL;DR: In this article , the authors identified the patterns of the epidemic process of COVID-19 in connection with the gender and age characteristics of hospitalized adults and established the sex and age groups most susceptible to hospitalization and mortality.
Insight into risk associated phenotypes behind COVID-19 from phenotype genome-wide association studies
Z. Chen,Koichi Matsuda +1 more
TL;DR: In this article , the authors analyzed 220 deep-phenotype genome-wide association data sets (159 diseases, 38 biomarkers and 23 medication usage) from BioBank Japan (BBJ), UK Biobank and FinnGen (n=628,000) to investigate pleiotropic effects of known COVID-19 risk associated single nucleotide variants.