Yuwei Jiang
University of Illinois at Chicago
35 Papers
39 Citations
Yuwei Jiang is an academic researcher from University of Illinois at Chicago. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 12, co-authored 21 publications. Previous affiliations of Yuwei Jiang include University of Texas Southwestern Medical Center & Baylor College of Medicine.
Chat about Author
Papers
Cellular Aging Contributes to Failure of Cold-Induced Beige Adipocyte Formation in Old Mice and Humans
Daniel C. Berry,Yuwei Jiang,Robert W. Arpke,Elizabeth L. Close,Aki Uchida,David W. Reading,Eric D. Berglund,Michael Kyba,Jonathan M. Graff +8 more
TL;DR: It is shown that aging murine and human beige progenitor cells display a cellular aging, senescence-like phenotype that accounts for their age-dependent failure, and this indicates that anti-aging orsenescence modalities could be a strategy to induce beiging, thereby improving metabolic health in aging humans.
205
Independent stem cell lineages regulate adipose organogenesis and adipose homeostasis.
TL;DR: Two phases of adipocyte generation that emanate from two independent adipose progenitor compartments: developmental and adult are found, which may provide a discrete therapeutic target for childhood and adult obesity.
171
Exercise-induced α-ketoglutaric acid stimulates muscle hypertrophy and fat loss through OXGR1-dependent adrenal activation.
Yexian Yuan,Pingwen Xu,Qing-Yan Jiang,Xingcai Cai,Tao Wang,Wentong Peng,Jiajie Sun,Canjun Zhu,Cha Zhang,Dong Yue,Zhihui He,Jinping Yang,Yuxian Zeng,Man Du,Fenglin Zhang,Lucas Ibrahimi,Sarah Schaul,Yuwei Jiang,Jiqiu Wang,Jia Sun,Qiao-Ping Wang,Liming Liu,Songbo Wang,Lina Wang,Xiaotong Zhu,Ping Gao,Qianyun Xi,Cong Yin,Fan Li,Guli Xu,Yongliang Zhang,Gang Shu +31 more
TL;DR: An unappreciated mechanism for the salutary effects of resistance exercise is revealed, using AKG as a systemically derived molecule for adrenal stimulation of muscle hypertrophy and fat loss.
60
miR-26 suppresses adipocyte progenitor differentiation and fat production by targeting Fbxl19
Asha Acharya,Daniel C. Berry,He Zhang,Yuwei Jiang,Benjamin T. Jones,Robert E. Hammer,Jonathan M. Graff,Joshua T. Mendell +7 more
TL;DR: A role for the broadly conserved miR-26 family of microRNAs as major regulators of APC differentiation and adipose tissue mass is reported and new potential therapeutic targets for obesity and related disorders are suggested.
A PPARγ transcriptional cascade directs adipose progenitor cell-niche interaction and niche expansion.
Yuwei Jiang,Daniel C. Berry,A-Young Jo,Wei Tang,Robert W. Arpke,Michael Kyba,Jonathan M. Graff +6 more
TL;DR: It is shown that the assembly and maintenance of the adipose vascular niche is controlled by PPARγ acting within APCs, and APC niche communication and retention are boosted by VEGF thereby impairing adipogenesis.