Yuting Fan
Sun Yat-sen University
8 Papers
19 Citations
Yuting Fan is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Apoptosis & Retinal pigment epithelium. The author has an hindex of 6, co-authored 8 publications.
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Papers
Protective effect of lutein on ARPE-19 cells upon H2O2-induced G2/M arrest
Huijun Liu,Weiwei Liu,Xin Zhou,Chongde Long,Xielan Kuang,Jie Hu,Yan Tang,Lanying Liu,Jia He,Zixin Huang,Yuting Fan,Guorong Jin,Qingjiong Zhang,Huangxuan Shen +13 more
TL;DR: It is demonstrated that lutein may be an effective antioxidant, which can be applied in the prevention of AMD, or other age-related diseases associated with oxidative damage.
ID2 protects retinal pigment epithelium cells from oxidative damage through p-ERK1/2/ID2/NRF2
Yuting Fan,Zixin Huang,Chongde Long,Jie Ning,Han Zhang,Xielan Kuang,Qingjiong Zhang,Huangxuan Shen +7 more
TL;DR: ID2 protects RPE cells from oxidative damage through the p-ERK1/2/ID2/NRF2 pathway and contributes to a better understanding of the mechanisms underlying oxidative stress in AMD and may present a new strategy for AMD treatment.
20
Curcumin Inhibits Proliferation and Epithelial-Mesenchymal Transition of Retinal Pigment Epithelial Cells Via Multiple Pathways.
Xin Zhou,Xielan Kuang,Chongde Long,Wei Liu,Yan Tang,Liangping Liu,Hongshan Liu,Jing He,Zhi-Shu Huang,Yuting Fan,Qingjiong Zhang,Huangxuan Shen +11 more
TL;DR: It is found that curcumin suppressed the AKT, MAPK and TGF-β pathways in RPE cells which may also affect proliferation and EMT, and provides the insights to broaden the application ofCurcumin in research and probably clinics.
19
Anti-tumor Drug THZ1 Suppresses TGFβ2-mediated EMT in Lens Epithelial Cells via Notch and TGFβ/Smad Signaling Pathway.
Jie Ning,Xinqi Ma,Chongde Long,Yuxiang Mao,Xielan Kuang,Zixin Huang,Yuting Fan,Han Zhang,Qing Xia,Renchun Wang,Yu Liang,Shuibin Lin,Qingjiong Zhang,Huangxuan Shen +13 more
TL;DR: The function and underlying mechanism of THz1 in regulation of EMT is uncovered, which provides a new perspective of the anti-tumor effect by THZ1 and may offer a novel treatment for PCO.
The inhibition of NOTCH2 reduces UVB-induced damage in retinal pigment epithelium cells.
Lanying Liu,Xin Zhou,Xielan Kuang,Chongde Long,Weiwei Liu,Yan Tang,Huijun Liu,Jia He,Zixin Huang,Yuting Fan,Qingjiong Zhang,Huangxuan Shen +11 more
TL;DR: It was identified that, in RPE cells, UVB increased intracellular reactive oxygen species (ROS) and induced cell apoptosis and Notch signaling was activated in a dose dependent manner and NOTCH2, but not NOTCH1, was demonstrated to be the major Notch receptor in R PE cells.