Yuta Kasagi
Kyushu University
40 Papers
112 Citations
Yuta Kasagi is an academic researcher from Kyushu University. The author has contributed to research in topics: Esophagectomy & Esophageal cancer. The author has an hindex of 11, co-authored 33 publications. Previous affiliations of Yuta Kasagi include Children's Hospital of Philadelphia & University of Pennsylvania.
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Papers
Three-Dimensional Organoids Reveal Therapy Resistance of Esophageal and Oropharyngeal Squamous Cell Carcinoma Cells.
Takashi Kijima,Hiroshi Nakagawa,Masataka Shimonosono,Prasanna M. Chandramouleeswaran,Takeo Hara,Varun Sahu,Yuta Kasagi,Osamu Kikuchi,Koji Tanaka,Veronique Giroux,Amanda B. Muir,Kelly A. Whelan,Shinya Ohashi,Seiji Naganuma,Andres J. Klein-Szanto,Yoshiaki Shinden,Ken Sasaki,Itaru Omoto,Yoshiaki Kita,Manabu Muto,Adam J. Bass,J. Alan Diehl,Gregory G. Ginsberg,Yuichiro Doki,Masaki Mori,Yasuto Uchikado,Takaaki Arigami,Narayan G. Avadhani,Devraj Basu,Anil K. Rustgi,Shoji Natsugoe +30 more
TL;DR: The single cell-based 3D organoid system may serve as a highly efficient platform to explore cancer therapeutics and therapy resistance mechanisms in conjunction with morphological and functional assays with implications for translation in personalized medicine.
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Prognostic Significance of Postoperative Complications After Curative Resection for Patients With Esophageal Squamous Cell Carcinoma
Hiroshi Saeki,Satoshi Tsutsumi,Hirotada Tajiri,Takafumi Yukaya,Ryosuke Tsutsumi,Sho Nishimura,Yu Nakaji,Kensuke Kudou,Shingo Akiyama,Yuta Kasagi,Ryota Nakanishi,Yuichiro Nakashima,Masahiko Sugiyama,Kippei Ohgaki,Hideto Sonoda,Eiji Oki,Yoshihiko Maehara +16 more
TL;DR: The development of postoperative complications is an independent disease-specific poor prognostic factor after curative resection for patients with less-advanced esophageal squamous cell carcinoma.
121
The Esophageal Organoid System Reveals Functional Interplay Between Notch and Cytokines in Reactive Epithelial Changes.
Yuta Kasagi,Prasanna M. Chandramouleeswaran,Kelly A. Whelan,Koji Tanaka,Veronique Giroux,Medha Sharma,Joshua Wang,Alain Benitez,Maureen DeMarshall,John W. Tobias,Kathryn E. Hamilton,Gary W. Falk,Jonathan M. Spergel,Jonathan M. Spergel,Andres J. Klein-Szanto,Anil K. Rustgi,Amanda B. Muir,Amanda B. Muir,Hiroshi Nakagawa +18 more
TL;DR: Esophageal 3D organoids serve as a novel platform to investigate regulatory mechanisms in squamous epithelial homeostasis in the context of EoE and other diseases, suggesting that this may contribute to epithelial phenotypes associated with disease.
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Discrimination of p53 immunohistochemistry-positive tumors by its staining pattern in gastric cancer
Koji Ando,Eiji Oki,Hiroshi Saeki,Zhao Yan,Yasuo Tsuda,Gen Hidaka,Yuta Kasagi,Hajime Otsu,Hiroyuki Kawano,Hiroyuki Kitao,Masaru Morita,Yoshihiko Maehara +11 more
TL;DR: P53‐scattered‐type staining tumors may reflect a functionally active nonmutated TP53 gene and distinguishing p53‐positive tumors by their staining pattern may be important in gastric cancer.
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Fibrostenotic eosinophilic esophagitis might reflect epithelial lysyl oxidase induction by fibroblast-derived TNF-α.
Yuta Kasagi,Kara K. Dods,Joshua X. Wang,Prasanna M. Chandramouleeswaran,Alain Benitez,Fiona Gambanga,Jonathan Kluger,Tokunbo Ashorobi,Jonathan Gross,John W. Tobias,Andres J. Klein-Szanto,Jonathan M. Spergel,Antonella Cianferoni,Antonella Cianferoni,Gary W. Falk,Kelly A. Whelan,Hiroshi Nakagawa,Amanda B. Muir +17 more
TL;DR: Esophageal epithelial LOX might have a role in the development of fibrosis with substantial translational implications andGene ontology and pathway analyses linked TNF-α and LOX expression in patients with EoE, which was validated in independent sets of patients with fibrostenotic conditions.
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