Yusuke Joki
Juntendo University
18 Papers
48 Citations
Yusuke Joki is an academic researcher from Juntendo University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 12, co-authored 15 publications. Previous affiliations of Yusuke Joki include Nagoya University.
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Papers
Myonectin Is an Exercise-Induced Myokine That Protects the Heart From Ischemia-Reperfusion Injury.
Naoya Otaka,Rei Shibata,Koji Ohashi,Yusuke Uemura,Takahiro Kambara,Takashi Enomoto,Hayato Ogawa,Masanori Ito,Hiroshi Kawanishi,Sonomi Maruyama,Yusuke Joki,Yusuke Fujikawa,Shingo Narita,Kazumasa Unno,Yoshiyuki Kawamoto,Takashi Murate,Toyoaki Murohara,Noriyuki Ouchi +17 more
TL;DR: The data indicate that myonectin functions as an endurance exercise-induced myokine which ameliorates acute myocardial ischemic injury by suppressing apoptosis and inflammation in the heart, suggesting that my onectin mediates some of the beneficial actions of exercise on cardiovascular health.
157
Adipose-derived factor CTRP9 attenuates vascular smooth muscle cell proliferation and neointimal formation
Yusuke Uemura,Rei Shibata,Koji Ohashi,Takashi Enomoto,Takahiro Kambara,Takashi Yamamoto,Yasuhiro Ogura,Daisuke Yuasa,Yusuke Joki,Kazuhiro Matsuo,Megumi Miyabe,Yoshiyuki Kataoka,Toyoaki Murohara,Noriyuki Ouchi +13 more
TL;DR: The present data indicate that CTRP 9 functions to attenuate neointimal formation following vascular injury through its ability to inhibit VSMC growth via cAMP‐dependent mechanism, suggesting that the therapeutic approaches to enhance CTRP9 production could be valuable for prevention of vascular restenosis after angioplasty.
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Muscle-derived follistatin-like 1 functions to reduce neointimal formation after vascular injury
Megumi Miyabe,Koji Ohashi,Rei Shibata,Yusuke Uemura,Yasuhiro Ogura,Daisuke Yuasa,Takahiro Kambara,Yoshiyuki Kataoka,Takashi Yamamoto,Kazuhiro Matsuo,Yusuke Joki,Takashi Enomoto,Satoko Hayakawa,Mizuho Hiramatsu-Ito,Masanori Ito,Maurice J.B. van den Hoff,Kenneth Walsh,Toyoaki Murohara,Noriyuki Ouchi +18 more
TL;DR: Findings indicate that muscle-derived Fstl1 attenuates neointimal formation in response to arterial injury by suppressing SMC proliferation through an AMPK-dependent mechanism.
Omentin functions to attenuate cardiac hypertrophic response
Kazuhiro Matsuo,Rei Shibata,Koji Ohashi,Takahiro Kambara,Yusuke Uemura,Mizuho Hiramatsu-Ito,Takashi Enomoto,Daisuke Yuasa,Yusuke Joki,Masanori Ito,Satoko Hayakawa,Hayato Ogawa,Shinji Kihara,Toyoaki Murohara,Noriyuki Ouchi +14 more
TL;DR: The attenuation of cardiac hypertrophy, fibrosis and ERK phosphorylation induced by transverse aortic constriction (TAC) or angiotensin II infusion is suggested, suggesting that omentin may represent a target molecule for the treatment of cardiachypertrophy.
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Cardiac Myocyte-Derived Follistatin-Like 1 Prevents Renal Injury in a Subtotal Nephrectomy Model
Satoko Hayakawa,Koji Ohashi,Rei Shibata,Yoshiyuki Kataoka,Megumi Miyabe,Takashi Enomoto,Yusuke Joki,Yuuki Shimizu,Takahiro Kambara,Yusuke Uemura,Daisuke Yuasa,Hayato Ogawa,Kazuhiro Matsuo,Mizuho Hiramatsu-Ito,Maurice J.B. van den Hoff,Kenneth Walsh,Toyoaki Murohara,Noriyuki Ouchi +17 more
TL;DR: The data suggest that FSTl1 functions in cardiorenal communication and that the lack of Fstl1 production by myocytes promotes glomerular and tubulointerstitial damage in the kidney.
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