Yunyun Wang
Nanjing Forestry University
29 Papers
42 Citations
Yunyun Wang is an academic researcher from Nanjing Forestry University. The author has contributed to research in topics: Chemistry & HeLa. The author has an hindex of 5, co-authored 27 publications.
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Papers
Design, synthesis and biological evaluation of novel β-pinene-based thiazole derivatives as potential anticancer agents via mitochondrial-mediated apoptosis pathway.
TL;DR: The data showed that compound 5g inhibited cell proliferation by inducing apoptosis and cell cycle arrest of Hela cells at the G0/G1 phase in a dose dependent manner, and indicated that compounds 5g induced apoptosis in Hela through ROS-mediated mitochondrial dysfunction signaling pathways.
73
Design, synthesis and anticancer activity of novel nopinone-based thiosemicarbazone derivatives
Yunyun Wang,Wen Gu,Shan Yu,Liu Fei,Xu Xu,Yiqin Yang,Qiangjian Zhang,Yan Zhang,Kuang Hongbo,Zhonglong Wang,Shifa Wang +10 more
TL;DR: In the in vitro anticancer activity, most derivatives showed considerable cytotoxic activity against three human cancer cell lines (MDA-MB-231, SMMC-7721 and Hela), and compound 4i exhibited most potent antitumor activity.
69
Two ultrafast responsive isolongifolanone based fluorescent probes for reversible and sensitive visualization of toxic BF3 in solution and in gas phase
Zhonglong Wang,Yan Zhang,Jie Song,Yunyun Wang,Mingxin Li,Yiqin Yang,Xu Xu,Haijun Xu,Shifa Wang +8 more
TL;DR: In this paper, two novel fluorescent probes MD1 and MD2 were designed and synthesized to detect BF3 based on natural and renewable isolongifolanone, and the probe MD1 exhibited a significant turn-on fluorescence enhancement.
18
Synthesis and antitumor activity of 2-isocamphanyl thiosemicarbazone derivatives via ROS-enhanced mitochondrial damage.
TL;DR: A series of 2-isocamphanyl thiosemicarbazone derivatives were synthesized and characterized by 1 H NMR, 13 C NMR and HRMS as mentioned in this paper.
17
Novel camphor-based pyrimidine derivatives induced cancer cell death through a ROS-mediated mitochondrial apoptosis pathway
TL;DR: A series of novel camphor-based pyrimidine derivatives (3a-3x) have been synthesized; their structures were determined by using conventional methods and compound 3f was further confirmed through single crystal XRD analysis as discussed by the authors.