Yung-Chi Cheng
Yale University
853 Papers
12.6K Citations
Yung-Chi Cheng is an academic researcher from Yale University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 87, co-authored 683 publications. Previous affiliations of Yung-Chi Cheng include University of Georgia & Vion Pharmaceuticals, Inc..
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Papers
Synthesis and Comparative Evaluation of Two Antiviral Agents: β-L-Fd4C and β-D-Fd4C.
Shu-Hui Chen,Stanley L. Lin,Ivan King,Tracy Spinka,Ginger E. Dutschman,Elizabeth A. Gullen,Yung-Chi Cheng,Terrence W. Doyle +7 more
TL;DR: In this article, the synthesis of beta-D-Fd4C was achieved in a stereoselective fashion from D-xylose, and the antiviral activity and cytotoxicity of the compound was compared with that of 3TC (Lamivudine) and 3TC(3TC) and the most potent antiviral agent.
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Synthesis of carbocyclic analogues of 4'-ethynyl- and 4'-cyano-d4T.
Hiroki Kumamoto,Keisuke Kato,Kazuhiro Haraguchi,Hiromichi Tanaka,Takao Nitanda,Masanori Baba,Ginger E. Dutschman,Yung-Chi Cheng +7 more
- 01 Nov 2004
TL;DR: Synthesis of carbocyclic analogues of 4'-ethynyl and cyano-d4T (4 and 5) was investigated and the ethynyl or cyano group was constructed by conversion of the ester function of key intermediate 13.
Correction: Virtual screening and optimization of Type II inhibitors of JAK2 from a natural product library
Dik-Lung Ma,Daniel Shiu-Hin Chan,Guo Wei,Hai-Jing Zhong,Hui Yang,Lai To Leung,Elizabeth A. Gullen,Pauline Chiu,Yung-Chi Cheng,Chung-Hang Leung +9 more
TL;DR: Correction for 'Virtual screening and optimization of Type II inhibitors of JAK2 from a natural product library' by Dik-Lung Ma et al., Chem.
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Synthesis and anti-HIV Activity of 4′-Cyano-2′,3′-didehydro-3′-deoxythymidine.
Kazuhiro Haraguchi,Yoshiharu Itoh,Shingo Takeda,Yosuke Honma,Hiromichi Tanaka,Takao Nitanda,Masanori Baba,Ginger E. Dutschman,Yung-Chi Cheng +8 more
TL;DR: In this paper, a new anti-HIV agent 4′−cyano−2′, 3′−didehydro−3′−deoxy−4′−(ethynyl)thymidine (9) was synthesized by allylic substitution of the 3′, 4−unsaturated nucleoside 14, having a leaving group at the 2′position, with cyanotrimethylsilane in the presence of SnCl4.
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Contrastive-Regularized U-Net for Video Anomaly Detection
TL;DR: In this paper , weakly supervised contrastive regularization is proposed to regularize the network, which learns more generalizable features by enforcing inter-class separability and intra-class compactness.
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