Yuling Chen
Humboldt University of Berlin
5 Papers
1 Citations
Yuling Chen is an academic researcher from Humboldt University of Berlin. The author has contributed to research in topics: Immune system & Antigen. The author has an hindex of 2, co-authored 5 publications. Previous affiliations of Yuling Chen include Leibniz Association.
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Papers
Hypoxia/HIF Modulates Immune Responses.
TL;DR: In this article, the effects of physiological and pathophysiological hypoxia on innate and adaptive immune activity are summarized and an overview on the control of immune response by cellular hypoxias-induced pathways with focus on the role of HIFs and discuss the opportunity to target hypoxiosis-sensitive pathways for the treatment of cancer and autoimmunity.
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Metabolism of T Lymphocytes in Health and Disease
Timo Gaber,Timo Gaber,Yuling Chen,Yuling Chen,Pierre-Louis Krauß,Pierre-Louis Krauß,Frank Buttgereit,Frank Buttgereit +7 more
TL;DR: Differences in metabolism in healthy and pathogenic T cells provide an explanation for dysfunctionality of T-cell responses in metabolic disorders, autoimmunity, and cancer.
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Functional Scaffold‐Free Bone Equivalents Induce Osteogenic and Angiogenic Processes in a Human In Vitro Fracture Hematoma Model
Moritz Pfeiffenberger,Moritz Pfeiffenberger,Alexandra Damerau,Alexandra Damerau,Igor Ponomarev,Christian H. Bucher,Yuling Chen,Yuling Chen,Dirk Barnewitz,Christa Thöne-Reineke,Paula Hoff,Frank Buttgereit,Frank Buttgereit,Timo Gaber,Timo Gaber,Annemarie Lang,Annemarie Lang +16 more
TL;DR: In this paper, scaffold-free bone-like constructs (SFBCs) were developed from bone marrow-derived mesenchymal stromal cells (MSCs) using a macro-scale mesenymal condensation approach, which revealed permeating mineralization characterized by increased bone volume and expression of osteogenic markers.
9
Production of IL-6 and Phagocytosis Are the Most Resilient Immune Functions in Metabolically Compromised Human Monocytes.
Pierre-Louis Krauss,Moritz Pfeiffenberger,Moritz Pfeiffenberger,Alexandra Damerau,Alexandra Damerau,Thomas Buttgereit,Yuling Chen,Yuling Chen,Timo Gaber,Timo Gaber,Frank Buttgereit,Frank Buttgereit +11 more
TL;DR: In this article, the potential of human monocytes to adapt to conditions of gradually inhibited oxidative phosphorylation (OXPHOS) under glucose free conditions was investigated, where myxothiazol, an inhibitor of mitochondrial respiration, was used to adjust two different levels of decreased mitochondrial ATP production.
6
An in vitro human-based fracture gap model – Mimicking the crosstalk between bone and immune cells
Moritz Pfeiffenberger,Moritz Pfeiffenberger,Alexandra Damerau,Alexandra Damerau,Igor Ponomarev,Christian H. Bucher,Yuling Chen,Yuling Chen,D. Barnewitz,Christa Thöne-Reineke,Paula Hoff,Frank Buttgereit,Frank Buttgereit,Timo Gaber,Timo Gaber,Annemarie Lang,Annemarie Lang +16 more
TL;DR: The in vitro 3D fracture gap model provides all osteogenic cues to induce the initial bone healing processes, which were further promoted by applying the osteoinductive deferoxamine (DFO) and demonstrated the importance of including the crosstalk between bone and immune cells.