Yuliang Ma
Cornell University
6 Papers
Yuliang Ma is an academic researcher from Cornell University. The author has contributed to research in topics: Aryl hydrocarbon receptor & Downregulation and upregulation. The author has an hindex of 6, co-authored 6 publications.
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Papers
Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models
Eloisi Caldas-Lopes,Leandro Cerchietti,James H. Ahn,Cristina C. Clement,Ana I. Robles,Anna Rodina,Kamalika Moulick,Tony Taldone,Alexander Gozman,Yunke Guo,Nian Wu,Elisa de Stanchina,Julie D. White,Steven S. Gross,Yuliang Ma,Lyuba Varticovski,Ari Melnick,Gabriela Chiosis +17 more
TL;DR: The results identify Hsp90 as a critical and multimodal target in this most difficult to treat breast cancer subtype and support the use of the Hsp 90 inhibitor PU-H71 for clinical trials involving patients with TNBC.
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Serum Metabolite Biomarkers Discriminate Healthy Smokers from COPD Smokers
TL;DR: Elevated levels of serum mFBP and additional disease-associated biomarkers point to a role for chronic inflammation, thrombosis, and oxidative stress in remodeling of the COPD airways.
Increases in Levels of Epoxyeicosatrienoic and Dihydroxyeicosatrienoic Acids (EETs and DHETs) in Liver and Heart In Vivo by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and in Hepatic EET:DHET Ratios by Cotreatment with TCDD and the Soluble Epoxide Hydrolase Inhibitor AUDA
TL;DR: An acetonitrile-based extraction procedure is reported that markedly increased the yield of arachidonic acid products by lipidomic analysis over a standard solid-phase extraction protocol, indicating that the in vivo profile of P450–arachidic acid metabolites can be modified for potential therapeutic intervention.
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Discovery and Biological Characterization of 1-(1H-indol-3-yl)-9H-pyrido[3,4-b]indole as an Aryl Hydrocarbon Receptor Activator Generated by Photoactivation of Tryptophan by Sunlight
Silvia Diani-Moore,Yuliang Ma,Erin Labitzke,Hui Tao,J. David Warren,Jared Anderson,Qiuying Chen,Steven S. Gross,Arleen B. Rifkind +8 more
TL;DR: In this paper, 1-(1H-indol-3-yl)-9H-pyrido[3,4-b]indole (IPI) was identified as a natural product of marine ascidia and now shown to be a TRP photoproduct with AHR-inducing properties.
ANSID: A Solid-Phase Proteomic Approach for Identification and Relative Quantification of Aromatic Nitration Sites
Tal Nuriel,Tal Nuriel,Julia Whitehouse,Yuliang Ma,Emily J. Mercer,Neil Brown,Steven S. Gross +6 more
TL;DR: Using the ANSID method, several endogenously nitrated proteins in rat brain and a total of 244 nitrated peptides from 145 proteins following in vitro exposure of rat brain homogenates to the nitrating agent peroxynitrite are identified.