Yukiko Kanatani
University of Toyama
13 Papers
72 Citations
Yukiko Kanatani is an academic researcher from University of Toyama. The author has contributed to research in topics: Insulin resistance & Adipose tissue. The author has an hindex of 9, co-authored 13 publications.
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Papers
Regulatory Mechanisms for Adipose Tissue M1 and M2 Macrophages in Diet-Induced Obese Mice
Shiho Fujisaka,Isao Usui,Agussalim Bukhari,Masashi Ikutani,Takeshi Oya,Yukiko Kanatani,Koichi Tsuneyama,Yoshinori Nagai,Kiyoshi Takatsu,Masaharu Urakaze,Masashi Kobayashi,Kazuyuki Tobe +11 more
TL;DR: It is found that the increased number of M2 ATMs after an HFD was associated with the upregulated expression of interleukin (IL)-10, an anti-inflammatory Th2 cytokine, in the adipocyte fraction as well as in adipose tissue.
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Treatment with SRT1720, a SIRT1 activator, ameliorates fatty liver with reduced expression of lipogenic enzymes in MSG mice
Yu Yamazaki,Isao Usui,Yukiko Kanatani,Yuji Matsuya,Koichi Tsuneyama,Shiho Fujisaka,Agussalim Bukhari,Hikari Suzuki,Satoko Senda,Shingo Imanishi,Kazuya Hirata,Manabu Ishiki,Ryuji Hayashi,Masaharu Urakaze,Hideo Nemoto,Masashi Kobayashi,Kazuyuki Tobe +16 more
TL;DR: SRT1720 treatment may reduce liver lipid accumulation, at least in part, by directly reducing the expressions of lipogenic genes in cultured HepG2 cells.
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Long-term Interleukin-1α Treatment Inhibits Insulin Signaling via IL-6 Production and SOCS3 Expression in 3T3-L1 Adipocytes
T. Uno,J. He,Isao Usui,Yukiko Kanatani,Agussalim Bukhari,Shiho Fujisaka,Yu Yamazaki,Hikari Suzuki,Minoru Iwata,Manabu Ishiki,Masaharu Urakaze,Tetsuro Haruta,H. Ogawa,Masashi Kobayashi +13 more
TL;DR: The results suggest that theIL-1alpha-mediated deterioration of insulin signaling is largely due to the IL-6 production and SOCS3 induction in 3T3-L1 adipocytes.
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Sirt1 activator induces proangiogenic genes in preadipocytes to rescue insulin resistance in diet-induced obese mice.
Allah Nawaz,Arshad Mehmood,Yukiko Kanatani,Tomonobu Kado,Yoshiko Igarashi,Akiko Takikawa,Seiji Yamamoto,Keisuke Okabe,Takashi Nakagawa,Kunimasa Yagi,Shiho Fujisaka,Kazuyuki Tobe +11 more
TL;DR: A novel role is suggested of SRT1720-induced Sirt1 activation in the induction of angiogenic genes in preadipocytes, thereby reducing inflammation and fibrosis in white adipose tissue (WAT) and promoting insulin sensitivity.
Angiotensin II enhances the increase in monocyte chemoattractant protein-1 production induced by tumor necrosis factor-α from 3T3-L1 preadipocytes
Sachie Asamizu,Masaharu Urakaze,Chikaaki Kobashi,Manabu Ishiki,Amal Khalifa Norel Din,Shiho Fujisaka,Yukiko Kanatani,Agussalim Bukahari,Satoko Senda,Hikari Suzuki,Yuh Yamazaki,Minoru Iwata,Isao Usui,Katsuya Yamazaki,Hirofumi Ogawa,Masashi Kobayashi,Kazuyuki Tobe +16 more
TL;DR: The results suggest that Ang II may serve as an additional stimulus on the TNF-alpha-induced MCP-1 production through the ERK-and p38MAPK-dependent pathways probably due to AP-1 activation.