Yujing Sheng
Soochow University (Suzhou)
9 Papers
Yujing Sheng is an academic researcher from Soochow University (Suzhou). The author has contributed to research in topics: Glioma & Malignant transformation. The author has an hindex of 5, co-authored 7 publications.
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Papers
The long non-coding RNA SNHG1 promotes glioma progression by competitively binding to miR-194 to regulate PHLDA1 expression.
Liang Liu,Yan Shi,Jia Shi,Haiyang Wang,Yujing Sheng,Qianqian Jiang,Hua Chen,Xiaojian Li,Jun Dong +8 more
TL;DR: This study shows that SNHG1 promotes glioma progression by competitively binding to miR-194 to regulate PHLDA1 expression, which may provide a novel therapeutic strategy forglioma.
Downregulation of miRNA-146a-5p promotes malignant transformation of mesenchymal stromal/stem cells by glioma stem-like cells.
Xingliang Dai,Xingliang Dai,Yunfei Wang,Xuchen Dong,Minfeng Sheng,Haiyang Wang,Jia Shi,Yujing Sheng,Liang Liu,Qianqian Jiang,Yanming Chen,Bingshan Wu,Xuejun Yang,Hongwei Cheng,Chunsheng Kang,Jun Dong +15 more
- 25 May 2020
TL;DR: It is suggested that downregulation of miR-146a-5p leads to overexpression of its target gene, heterogeneous nuclear ribonucleoprotein D, thereby promoting malignant transformation of MSCs during interactions with GSCs.
Overexpression of GBP1 predicts poor prognosis and promotes tumor growth in human glioblastoma multiforme
Xiaoyan Ji,Hanting Zhu,Xiaoxiao Dai,Yujun Xi,Yujing Sheng,Ce Gao,Hairui Liu,Xue Yanping,Jiachi Liu,Jia Shi,Yongsheng Zhang,Yanming Chen,Xingliang Dai,Ming Li,Aidong Wang,Jun Dong +15 more
TL;DR: It is demonstrated that high level expression of GBP1 is significantly correlated with progression and prognosis in GBMs and may serve as a novel prognostic biomarker and a potential therapeutic target for gliomas.
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Prognostic value of NUSAP1 in progression and expansion of glioblastoma multiforme.
Zhiyuan Qian,Yuping Li,Jiawei Ma,Xue Yanping,Yujun Xi,Lei Hong,Xiaoxiao Dai,Yongsheng Zhang,Xiaoyan Ji,Yanming Chen,Minfeng Sheng,Yujing Sheng,Lin Yang,Jiachi Liu,Xingliang Dai,Jia Shi,Tao Xie,Jun Dong +17 more
TL;DR: It is demonstrated that NUSAP1 was significantly up-regulated in GBM tissues compared with adult non-tumor brain tissues both in a validated cohort and a TCGA cohort, and knockdown of N USAP1 revealed its regulation on G2/M progression and cell proliferation (both in vitro and in vivo).
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Human glioma stem-like cells induce malignant transformation of bone marrow mesenchymal stem cells by activating TERT expression
Yaodong Zhao,Jinsheng Chen,Xingliang Dai,Honghua Cai,Xiaoyan Ji,Yujing Sheng,Hairui Liu,Lin Yang,Yanming Chen,Dengguo Xi,Minfeng Sheng,Xue Yanping,Jia Shi,Jiachi Liu,Xiao-Nan Li,Jun Dong +15 more
TL;DR: GSCs induce malignant transformation of BMSCs by activating TERT expression in B MSCs, suggesting paracrine factors from GSCs induced their malignant Transformation.
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