Yujeong Jeong
KAIST
18 Papers
85 Citations
Yujeong Jeong is an academic researcher from KAIST. The author has contributed to research in topics: PI3K/AKT/mTOR pathway & Angiogenesis. The author has an hindex of 10, co-authored 14 publications.
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Papers
Design and Synthesis of Imidazopyridine Analogues as Inhibitors of Phosphoinositide 3-Kinase Signaling and Angiogenesis
TL;DR: A new series of imidazo[1,2-a]pyridine derivatives are designed and synthesized as PI3Kα inhibitors through the fragment-growing strategy and showed good activity in cellular proliferation and apoptosis assays.
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Identification of β-lapachone analogs as novel MALT1 inhibitors to treat an aggressive subtype of diffuse large B-cell lymphoma
Sang Min Lim,Yujeong Jeong,Suhyun Lee,Honggu Im,Hyun Seop Tae,Byung Gyu Kim,Hee Dong Park,Jonghoon Park,Sungwoo Hong +8 more
TL;DR: A new class of MALT1 inhibitors developed by high-throughput screening and structure-based drug design exhibited potent antiproliferative activity to OCI-LY3 cell line and inhibited the cleavage of CYLD mediated MALT 1.
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Ru(II)-Catalyzed Site-Selective Hydroxylation of Flavone and Chromone Derivatives: The Importance of the 5-Hydroxyl Motif for the Inhibition of Aurora Kinases.
TL;DR: The molecular docking simulations indicate that the formation of bidentate H-bonding patterns in the hinge regions between the 5-hydroxyflavonoids and Ala213 was the significant binding force, which is consistent with experimental and computational findings.
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A novel imidazopyridine derivative, HS-106, induces apoptosis of breast cancer cells and represses angiogenesis by targeting the PI3K/mTOR pathway
Guang-Yong Li,Guang-Yong Li,Kyung Hee Jung,Hyunseung Lee,Mi Kwon Son,Ju-Hyeon Seo,Sang-Won Hong,Yujeong Jeong,Sungwoo Hong,Soon-Sun Hong +9 more
TL;DR: The results show that HS-106 may be an effective novel therapeutic candidate in clinical trials as a potential treatment for human breast cancers or other advanced malignancies with aberrant PI3K/Akt/mTOR signaling.
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Ligand-free monophasic CuPd alloys endows boosted reaction kinetics toward energy-efficient hydrogen fuel production paired with hydrazine oxidation
Yujeong Jeong,Shankar Naik Shreyanka,Yiseul Yu,Jayaraman Theerthagiri,Seung Jun Lee,Pau Loke Show,Hyun Chul Choi,Myong Yong Choi +7 more
TL;DR: In this article , the semiconductor and adsorption characteristics of Cu, interlaced by Pd2+ solution on the Pd surface by pulsed laser ablation (PLA) in methanol, are selectively altered to maximize cathodic HER and anodic HzOR performance.
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